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<p>The Human Fertilisation and Embryology Authority (HFEA) has advised that it is
a requirement for all its licensed centres to report cases of ovarian hyperstimulation
syndrome (OHSS) that require a hospital admission and have a severity grading of severe
or critical. Some centres also report cases of mild or moderate OHSS.</p><p>Between
1 October 2013 and 31 October 2018 there were 792 OHSS cases reported requiring hospital
admission (391 of which were classified as severe and 401 classified as mild/moderate).
HFEA does not hold data on whether these admissions were out of hours or via emergency
admission. Following the reports of cases of severe or critical OHSS, the centres
are required to conduct a root cause analysis and submit a report to the HFEA. The
HFEA publishes an annual report on incidents, of which OHSS cases form a part.</p><p>From
April 2018 the HFEA has required its licensed centres to provide it with more information
about treatment provided to patients in cases of severe OHSS. This information will
be collected for two years and will then be analysed.</p><p>The HFEA has also advised
that following discussions with key stakeholders it has reached a view that the Hospital
Episode Statistics data may include a mislabelling of cases of OHSS. A paper presented
to Authority members in January 2018 sets out the work undertaken to examine the reporting
of severe and critical OHSS. A copy of <em>Ovarian Hyperstimulation Syndrome</em>
is attached. HFEA does not hold estimates of the number of hospital admissions that
may have been incorrectly coded for OHSS.</p><p>HFEA is continuing to work to better
understand the incidence of OHSS, reduce its occurrence and improve reporting.</p><p><strong>
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