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<p>The Human Fertilisation and Embryology Authority (HFEA) has advised that it and
all of the relevant professional bodies support the <em>One at a time</em> initiative,
which aims to reduce the incidence of multiple births following in-vitro fertilisation
(IVF). The consensus statement signed in 2011 states that “Multiple births is the
single biggest risk to the health and welfare of children born following fertility
treatment”:</p><p> </p><p> </p><p> </p><p><a href="http://www.oneatatime.org.uk/images/2011-05_Multiple_Births_Consensus_Statement_-_FINAL.pdf"
target="_blank">www.oneatatime.org.uk/images/2011-05_Multiple_Births_Consensus_Statement_-_FINAL.pdf</a></p><p>
</p><p> </p><p> </p><p>The HFEA holds records on foetal reductions carried out in
the first trimester and early in the second trimester following each cycle of IVF
or donor insemination in the UK.</p><p> </p><p> </p><p> </p><p>When developing its
policy on multiple births the HFEA commissioned an Expert Group on Multiple Births
after IVF, which concluded that the prevention of multiple pregnancies through single
embryo transfer should be preferred to multifetal pregnancy reduction.</p><p> </p><p><strong>
</strong></p><p> </p><p>Information on average mortality rates for singleton, twin
and triplet pregnancies is not collected centrally. The information that is available
is shown in the following table.</p><p> </p><p> </p><p> </p><p> </p><p> </p><p><strong>
</strong></p><p> </p><table><tbody><tr><td colspan="13"><p> </p><p> </p><p>Stillbirths
and linked infant deaths rates: babies born in each year 2002 to 2011, plurality,</p><p>England
and Wales<sup> 1,2,3,4</sup></p></td></tr><tr><td> </td><td> </td><td> </td><td> </td><td>
</td><td> </td><td> </td><td> </td><td> </td><td> </td><td> </td><td> </td><td> </td></tr><tr><td><p>
</p></td><td colspan="3"><p>Stillbirth</p></td><td><p> </p></td><td colspan="3"><p>Infant</p></td><td>
</td><td> </td><td> </td><td> </td><td> </td></tr><tr><td><p>Year</p></td><td><p>Singletons</p></td><td><p>Twins</p></td><td><p>Triplets</p></td><td><p>
</p></td><td><p>Singletons</p></td><td><p>Twins</p></td><td><p>Triplets</p></td><td>
</td><td> </td><td> </td><td> </td><td> </td></tr><tr><td><p>2002</p></td><td><p>5.3</p></td><td><p>15.7</p></td><td><p>44.6</p></td><td>
</td><td><p>4.7</p></td><td><p>23.1</p></td><td><p>40.6</p></td><td> </td><td> </td><td>
</td><td> </td><td> </td></tr><tr><td><p>2003</p></td><td><p>5.4</p></td><td><p>17.6</p></td><td><p>52.5</p></td><td>
</td><td><p>4.7</p></td><td><p>23.5</p></td><td><p>63.7</p></td><td> </td><td> </td><td>
</td><td> </td><td> </td></tr><tr><td><p>2004</p></td><td><p>5.4</p></td><td><p>14.8</p></td><td><p>51.8</p></td><td>
</td><td><p>4.5</p></td><td><p>21.6</p></td><td><p>61.8</p></td><td> </td><td> </td><td>
</td><td> </td><td> </td></tr><tr><td><p>2005</p></td><td><p>5.1</p></td><td><p>13.2</p></td><td><p>29.7</p></td><td><p>u</p></td><td><p>4.4</p></td><td><p>23.5</p></td><td><p>54.1</p></td><td>
</td><td> </td><td> </td><td> </td><td> </td></tr><tr><td><p>2006</p></td><td><p>5.1</p></td><td><p>11.8</p></td><td><p>24.2</p></td><td><p>u</p></td><td><p>4.4</p></td><td><p>21.7</p></td><td><p>67.0</p></td><td>
</td><td> </td><td> </td><td> </td><td> </td></tr><tr><td><p>2007</p></td><td><p>5.0</p></td><td><p>11.2</p></td><td><p>19.7</p></td><td><p>u</p></td><td><p>4.2</p></td><td><p>19.9</p></td><td><p>50.3</p></td><td>
</td><td> </td><td> </td><td> </td><td> </td></tr><tr><td><p>2008</p></td><td><p>4.9</p></td><td><p>11.6</p></td><td><p>28.7</p></td><td><p>u</p></td><td><p>4.1</p></td><td><p>20.0</p></td><td><p>55.2</p></td><td>
</td><td> </td><td> </td><td> </td><td> </td></tr><tr><td><p>2009</p></td><td><p>4.9</p></td><td><p>12.2</p></td><td><p>31.5</p></td><td><p>u</p></td><td><p>4.0</p></td><td><p>20.1</p></td><td><p>34.9</p></td><td><p>u</p></td><td>
</td><td> </td><td> </td><td> </td></tr><tr><td><p>2010</p></td><td><p>4.9</p></td><td><p>11.4</p></td><td><p>15.8</p></td><td><p>u</p></td><td><p>3.8</p></td><td><p>18.4</p></td><td><p>62.1</p></td><td>
</td><td> </td><td> </td><td> </td><td> </td></tr><tr><td><p>2011</p></td><td><p>5.0</p></td><td><p>10.9</p></td><td><p>15.5</p></td><td><p>u</p></td><td><p>3.7</p></td><td><p>18.8</p></td><td><p>21.7</p></td><td><p>u</p></td><td>
</td><td> </td><td> </td><td> </td></tr><tr><td colspan="9"><p> </p><p><em> </em></p><p><em>Notes:</em></p><p>
</p><p>1 Stillbirths per 1,000 live births and stillbirths. Infant deaths per 1,000
live births.</p></td><td> </td><td> </td><td> </td><td> </td></tr><tr><td colspan="4"><p>2
Excludes babies born to non-residents.</p></td><td> </td><td> </td><td> </td><td>
</td><td> </td><td> </td><td> </td><td> </td><td> </td></tr><tr><td colspan="12" rowspan="2"><p>3
Rates based on between 3 and 19 deaths (inclusive) are distinguished by 'u' as a warning
that their reliability may be affected by the small number of events.</p><p>4 Information
is not available for Scotland and Northern Ireland.</p></td><td> </td></tr><tr><td>
</td></tr><tr><td colspan="4"><p><em> </em></p><p><em>Source:</em> Office for National
Statistics</p></td><td> </td><td> </td><td> </td><td> </td><td> </td><td> </td><td>
</td><td> </td><td> </td></tr></tbody></table><p> </p>
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