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114517
registered interest false more like this
date less than 2014-11-05more like thismore than 2014-11-05
answering body
Department of Health more like this
answering dept id 17 more like this
answering dept short name Health more like this
answering dept sort name Health more like this
hansard heading Ovarian Hyperstimulation Syndrome more like this
house id 2 more like this
legislature
25277
pref label House of Lords more like this
question text To ask Her Majesty’s Government, further to the Written Answer by the Parliamentary Under-Secretary of State for Public Health, Jane Ellison, on 12 September (HC Deb, col 750W), whether data regarding the cohort of patients that may develop ovarian hyperstimulation syndrome as described in the journals Human Fertility (volume 10, issue 3, pages 183–7) or Fertility and Sterility (volume 101, issue 4, pages 967–973) were shared with the Human Fertilisation and Embryology Authority (HFEA); and what assessment the HFEA has made of those studies. more like this
tabling member printed
Lord Alton of Liverpool more like this
uin HL2690 more like this
answer
answer
is ministerial correction false more like this
date of answer less than 2014-11-18more like thismore than 2014-11-18
answer text <p>The Human Fertilisation and Embryology Authority (HFEA) has advised that, with regard to the Human Fertility journal article, it has nothing to add to the answers given to the noble Lord on 22 October 2008 (Official Report WA110), 9 July 2012 (Official Report, cols. WA 202-3) and 8 January 2013 (WA23). Data regarding the cohort of patients described in Fertility and Sterility (volume 101, issue 4, pages 967–973) were not shared with the HFEA. However, the HFEA has access to the published article.</p><p> </p><p> </p><p> </p><p>It would be for clinicians and professional bodies to decide on the evidence required to predict the cohort of patients that may develop ovarian hyperstimulation syndrome and to treat symptoms in accordance with guidelines.</p><p> </p><p> </p><p> </p><p>As outlined in the answer given on 23 Jan 2013 (Official Report WA217), the HFEA would refer to evidence based guidelines, produced by the National Institute for Health and Care Excellence, on these matters.</p><p> </p>
answering member printed Earl Howe more like this
grouped question UIN HL2640 more like this
question first answered
less than 2014-11-18T12:39:40.517Zmore like thismore than 2014-11-18T12:39:40.517Z
answering member
2000
label Biography information for Earl Howe more like this
tabling member
738
label Biography information for Lord Alton of Liverpool more like this
114518
registered interest false more like this
date less than 2014-11-05more like thismore than 2014-11-05
answering body
Department of Health more like this
answering dept id 17 more like this
answering dept short name Health more like this
answering dept sort name Health more like this
hansard heading Ovarian Hyperstimulation Syndrome more like this
house id 2 more like this
legislature
25277
pref label House of Lords more like this
question text To ask Her Majesty’s Government, further to the Written Answers by the Parliamentary Under-Secretary of State for Public Health, Jane Ellison, on 11 September (HC Deb, cols 664–5W) and on 12 September (HC Deb, col 750W), how the assessment was made that if "mitochondria donation was permitted in treatment it is not anticipated that this will impact on the incidence of ovarian hyperstimulation syndrome" in the absence of an evidence base to predict the cohort of patients that may develop ovarian hyperstimulation syndrome. more like this
tabling member printed
Lord Alton of Liverpool more like this
uin HL2691 more like this
answer
answer
is ministerial correction false more like this
date of answer less than 2014-11-17more like thismore than 2014-11-17
answer text <p>Further to answers given on 12 September (HC Deb, col 750w) the Human Fertilisation and Embryology Authority (HFEA) has advised that if mitochondrial donation was permitted in treatment it is not anticipated that this would impact on the incidence of ovarian hyper stimulation syndrome (OHSS). This is because any egg donation or collection processes necessary for mitochondrial donation would be carried out at HFEA licensed fertility clinics in line with the guidance outlined in the HFEA Code of Practice. Mitochondrial donation raises no new issues in respect of OHSS as the women who may donate eggs will be subject to the same protocols as those donating to fertility treatment.</p><p> </p> more like this
answering member printed Earl Howe more like this
question first answered
less than 2014-11-17T12:06:01.787Zmore like thismore than 2014-11-17T12:06:01.787Z
answering member
2000
label Biography information for Earl Howe more like this
tabling member
738
label Biography information for Lord Alton of Liverpool more like this
106168
registered interest false more like this
date less than 2014-11-04more like thismore than 2014-11-04
answering body
Department of Health more like this
answering dept id 17 more like this
answering dept short name Health more like this
answering dept sort name Health more like this
hansard heading Ovarian Hyperstimulation Syndrome more like this
house id 2 more like this
legislature
25277
pref label House of Lords more like this
question text To ask Her Majesty’s Government, further to the Written Answer by the Parliamentary Under-Secretary of State for Public Health, Jane Ellison, on 12 September (HC Deb, col 750W), what evidence would be required to predict the cohort of patients that may develop ovarian hyperstimulation syndrome; whether the incidence of ovarian hyperstimulation syndrome would be part of any such evidence base; and, if not, why not. more like this
tabling member printed
Lord Alton of Liverpool more like this
uin HL2640 more like this
answer
answer
is ministerial correction false more like this
date of answer less than 2014-11-18more like thismore than 2014-11-18
answer text <p>The Human Fertilisation and Embryology Authority (HFEA) has advised that, with regard to the Human Fertility journal article, it has nothing to add to the answers given to the noble Lord on 22 October 2008 (Official Report WA110), 9 July 2012 (Official Report, cols. WA 202-3) and 8 January 2013 (WA23). Data regarding the cohort of patients described in Fertility and Sterility (volume 101, issue 4, pages 967–973) were not shared with the HFEA. However, the HFEA has access to the published article.</p><p> </p><p> </p><p> </p><p>It would be for clinicians and professional bodies to decide on the evidence required to predict the cohort of patients that may develop ovarian hyperstimulation syndrome and to treat symptoms in accordance with guidelines.</p><p> </p><p> </p><p> </p><p>As outlined in the answer given on 23 Jan 2013 (Official Report WA217), the HFEA would refer to evidence based guidelines, produced by the National Institute for Health and Care Excellence, on these matters.</p><p> </p>
answering member printed Earl Howe more like this
grouped question UIN HL2690 more like this
question first answered
less than 2014-11-18T12:39:40.423Zmore like thismore than 2014-11-18T12:39:40.423Z
answering member
2000
label Biography information for Earl Howe more like this
tabling member
738
label Biography information for Lord Alton of Liverpool more like this
106169
registered interest false more like this
date less than 2014-11-04more like thismore than 2014-11-04
answering body
Department of Health more like this
answering dept id 17 more like this
answering dept short name Health more like this
answering dept sort name Health more like this
hansard heading Ovarian Hyperstimulation Syndrome more like this
house id 2 more like this
legislature
25277
pref label House of Lords more like this
question text To ask Her Majesty’s Government, further to the Written Answers by the Parliamentary Under-Secretary of State for Public Health, Jane Ellison, on 11 September (HC Deb, cols 664–5W) and on 12 September (HC Deb, col 750W), how it is anticipated that proposed interventions for mitochondrial disease would not impact on the incidence of ovarian hyperstimulation syndrome. more like this
tabling member printed
Lord Alton of Liverpool more like this
uin HL2641 more like this
answer
answer
is ministerial correction false more like this
date of answer less than 2014-11-17more like thismore than 2014-11-17
answer text <p>Further to answers given on 12 September (HC Deb, col 750w) the Human Fertilisation and Embryology Authority (HFEA) has advised that if mitochondrial donation was permitted in treatment it is not anticipated that this would impact on the incidence of ovarian hyper stimulation syndrome (OHSS). This is because any egg donation or collection processes necessary for mitochondrial donation would be carried out at HFEA licensed fertility clinics in line with the guidance outlined in the HFEA Code of Practice. Mitochondrial donation raises no new issues in respect of OHSS as the women who may donate eggs will be subject to the same protocols as those donating to fertility treatment.</p><p> </p> more like this
answering member printed Earl Howe more like this
question first answered
less than 2014-11-17T12:08:24.3Zmore like thismore than 2014-11-17T12:08:24.3Z
answering member
2000
label Biography information for Earl Howe more like this
tabling member
738
label Biography information for Lord Alton of Liverpool more like this
106170
registered interest false more like this
date less than 2014-11-04more like thismore than 2014-11-04
answering body
Department of Health more like this
answering dept id 17 more like this
answering dept short name Health more like this
answering dept sort name Health more like this
hansard heading IVF more like this
house id 2 more like this
legislature
25277
pref label House of Lords more like this
question text To ask Her Majesty’s Government, further to the remarks by the Parliamentary Under-Secretary of State for Public Health, Jane Ellison, on 1 September (HC Deb, cols 119–122), how many of the mitochondrial diseases listed in Annex D of the consultation document entitled "Mitochondrial Donation" are included in the Human DNA Polymerase Gamma Mutation Database maintained by the National Institutes of Health in the USA; and what assessment they have made of the causal relationship between mutations affecting DNA Polymerase Gamma and disease-associated mitochondrial DNA mutations. more like this
tabling member printed
Lord Alton of Liverpool more like this
uin HL2642 more like this
answer
answer
is ministerial correction false more like this
date of answer less than 2014-11-17more like thismore than 2014-11-17
answer text <p>The mitochondrial diseases listed in Annex D of the “<em>Mitochondrial Donation</em>” consultation document are diseases caused by an inherited mutation in mitochondrial DNA that results in faulty mitochondria. In contrast, the mitochondrial diseases listed in the Human DNA Polymerase Gamma Mutation Database are secondary disorders whereby faulty mitochondria arise from a nuclear gene defect. As such the primary mitochondrial DNA diseases listed in Annex D are distinct from those diseases listed in the Human DNA Polymerase Gamma Database, caused by a nuclear gene mutation.</p><p> </p><p> </p><p> </p><p>The proposed mitochondrial donation techniques would only be used for patients that have inherited mitochondrial DNA mutations and could not be used for those diseases in which faulty mitochondria arise from a nuclear gene mutation, as this mutation would still be inherited by the resulting child from the parents nuclear DNA.</p><p> </p> more like this
answering member printed Earl Howe more like this
question first answered
less than 2014-11-17T12:09:54.457Zmore like thismore than 2014-11-17T12:09:54.457Z
answering member
2000
label Biography information for Earl Howe more like this
tabling member
738
label Biography information for Lord Alton of Liverpool more like this
106172
registered interest false more like this
date less than 2014-11-04more like thismore than 2014-11-04
answering body
Department of Health more like this
answering dept id 17 more like this
answering dept short name Health more like this
answering dept sort name Health more like this
hansard heading IVF more like this
house id 2 more like this
legislature
25277
pref label House of Lords more like this
question text To ask Her Majesty’s Government, further to the Written Answer by Earl Howe on 23 January 2013 (HL4388), whether the Human Fertilisation and Embryology Authority still considers that multiple pregnancy poses "the single greatest health risk associated with fertility treatment"; what records they hold on foetal reduction in the first trimester and early in the second trimester; what assessment they have made of the impact of such procedures on the incidence of complications otherwise associated with multiple pregnancy; and what was the average mortality rate of (1) singleton, (2) twin, and (3) triplet, pregnancies in the United Kingdom over each year of the past decade for which records are available. more like this
tabling member printed
Lord Alton of Liverpool more like this
uin HL2643 more like this
answer
answer
is ministerial correction false more like this
date of answer less than 2014-11-17more like thismore than 2014-11-17
answer text <p>The Human Fertilisation and Embryology Authority (HFEA) has advised that it and all of the relevant professional bodies support the <em>One at a time</em> initiative, which aims to reduce the incidence of multiple births following in-vitro fertilisation (IVF). The consensus statement signed in 2011 states that “Multiple births is the single biggest risk to the health and welfare of children born following fertility treatment”:</p><p> </p><p> </p><p> </p><p><a href="http://www.oneatatime.org.uk/images/2011-05_Multiple_Births_Consensus_Statement_-_FINAL.pdf" target="_blank">www.oneatatime.org.uk/images/2011-05_Multiple_Births_Consensus_Statement_-_FINAL.pdf</a></p><p> </p><p> </p><p> </p><p>The HFEA holds records on foetal reductions carried out in the first trimester and early in the second trimester following each cycle of IVF or donor insemination in the UK.</p><p> </p><p> </p><p> </p><p>When developing its policy on multiple births the HFEA commissioned an Expert Group on Multiple Births after IVF, which concluded that the prevention of multiple pregnancies through single embryo transfer should be preferred to multifetal pregnancy reduction.</p><p> </p><p><strong> </strong></p><p> </p><p>Information on average mortality rates for singleton, twin and triplet pregnancies is not collected centrally. The information that is available is shown in the following table.</p><p> </p><p> </p><p> </p><p> </p><p> </p><p><strong> </strong></p><p> </p><table><tbody><tr><td colspan="13"><p> </p><p> </p><p>Stillbirths and linked infant deaths rates: babies born in each year 2002 to 2011, plurality,</p><p>England and Wales<sup> 1,2,3,4</sup></p></td></tr><tr><td> </td><td> </td><td> </td><td> </td><td> </td><td> </td><td> </td><td> </td><td> </td><td> </td><td> </td><td> </td><td> </td></tr><tr><td><p> </p></td><td colspan="3"><p>Stillbirth</p></td><td><p> </p></td><td colspan="3"><p>Infant</p></td><td> </td><td> </td><td> </td><td> </td><td> </td></tr><tr><td><p>Year</p></td><td><p>Singletons</p></td><td><p>Twins</p></td><td><p>Triplets</p></td><td><p> </p></td><td><p>Singletons</p></td><td><p>Twins</p></td><td><p>Triplets</p></td><td> </td><td> </td><td> </td><td> </td><td> </td></tr><tr><td><p>2002</p></td><td><p>5.3</p></td><td><p>15.7</p></td><td><p>44.6</p></td><td> </td><td><p>4.7</p></td><td><p>23.1</p></td><td><p>40.6</p></td><td> </td><td> </td><td> </td><td> </td><td> </td></tr><tr><td><p>2003</p></td><td><p>5.4</p></td><td><p>17.6</p></td><td><p>52.5</p></td><td> </td><td><p>4.7</p></td><td><p>23.5</p></td><td><p>63.7</p></td><td> </td><td> </td><td> </td><td> </td><td> </td></tr><tr><td><p>2004</p></td><td><p>5.4</p></td><td><p>14.8</p></td><td><p>51.8</p></td><td> </td><td><p>4.5</p></td><td><p>21.6</p></td><td><p>61.8</p></td><td> </td><td> </td><td> </td><td> </td><td> </td></tr><tr><td><p>2005</p></td><td><p>5.1</p></td><td><p>13.2</p></td><td><p>29.7</p></td><td><p>u</p></td><td><p>4.4</p></td><td><p>23.5</p></td><td><p>54.1</p></td><td> </td><td> </td><td> </td><td> </td><td> </td></tr><tr><td><p>2006</p></td><td><p>5.1</p></td><td><p>11.8</p></td><td><p>24.2</p></td><td><p>u</p></td><td><p>4.4</p></td><td><p>21.7</p></td><td><p>67.0</p></td><td> </td><td> </td><td> </td><td> </td><td> </td></tr><tr><td><p>2007</p></td><td><p>5.0</p></td><td><p>11.2</p></td><td><p>19.7</p></td><td><p>u</p></td><td><p>4.2</p></td><td><p>19.9</p></td><td><p>50.3</p></td><td> </td><td> </td><td> </td><td> </td><td> </td></tr><tr><td><p>2008</p></td><td><p>4.9</p></td><td><p>11.6</p></td><td><p>28.7</p></td><td><p>u</p></td><td><p>4.1</p></td><td><p>20.0</p></td><td><p>55.2</p></td><td> </td><td> </td><td> </td><td> </td><td> </td></tr><tr><td><p>2009</p></td><td><p>4.9</p></td><td><p>12.2</p></td><td><p>31.5</p></td><td><p>u</p></td><td><p>4.0</p></td><td><p>20.1</p></td><td><p>34.9</p></td><td><p>u</p></td><td> </td><td> </td><td> </td><td> </td></tr><tr><td><p>2010</p></td><td><p>4.9</p></td><td><p>11.4</p></td><td><p>15.8</p></td><td><p>u</p></td><td><p>3.8</p></td><td><p>18.4</p></td><td><p>62.1</p></td><td> </td><td> </td><td> </td><td> </td><td> </td></tr><tr><td><p>2011</p></td><td><p>5.0</p></td><td><p>10.9</p></td><td><p>15.5</p></td><td><p>u</p></td><td><p>3.7</p></td><td><p>18.8</p></td><td><p>21.7</p></td><td><p>u</p></td><td> </td><td> </td><td> </td><td> </td></tr><tr><td colspan="9"><p> </p><p><em> </em></p><p><em>Notes:</em></p><p> </p><p>1 Stillbirths per 1,000 live births and stillbirths. Infant deaths per 1,000 live births.</p></td><td> </td><td> </td><td> </td><td> </td></tr><tr><td colspan="4"><p>2 Excludes babies born to non-residents.</p></td><td> </td><td> </td><td> </td><td> </td><td> </td><td> </td><td> </td><td> </td><td> </td></tr><tr><td colspan="12" rowspan="2"><p>3 Rates based on between 3 and 19 deaths (inclusive) are distinguished by 'u' as a warning that their reliability may be affected by the small number of events.</p><p>4 Information is not available for Scotland and Northern Ireland.</p></td><td> </td></tr><tr><td> </td></tr><tr><td colspan="4"><p><em> </em></p><p><em>Source:</em> Office for National Statistics</p></td><td> </td><td> </td><td> </td><td> </td><td> </td><td> </td><td> </td><td> </td><td> </td></tr></tbody></table><p> </p>
answering member printed Earl Howe more like this
question first answered
less than 2014-11-17T12:11:34.89Zmore like thismore than 2014-11-17T12:11:34.89Z
answering member
2000
label Biography information for Earl Howe more like this
tabling member
738
label Biography information for Lord Alton of Liverpool more like this
106173
registered interest false more like this
date less than 2014-11-04more like thismore than 2014-11-04
answering body
Department of Health more like this
answering dept id 17 more like this
answering dept short name Health more like this
answering dept sort name Health more like this
hansard heading IVF more like this
house id 2 more like this
legislature
25277
pref label House of Lords more like this
question text To ask Her Majesty’s Government whether they will place in the Library of the House a full copy of the correspondence between the Human Fertilisation and Embryology Authority and the authors of "Pregnancy derived from human nuclear transfer" published in Fertility &amp; Sterility (2003, Vol. 80, Supplement 3). more like this
tabling member printed
Lord Alton of Liverpool more like this
uin HL2644 more like this
answer
answer
is ministerial correction false more like this
date of answer less than 2014-11-18more like thismore than 2014-11-18
answer text <p>The Human Fertilisation and Embryology Authority has advised that neither its members nor its executive have been in correspondence with the authors of the abstract referred to.</p><p> </p> more like this
answering member printed Earl Howe more like this
question first answered
less than 2014-11-18T15:49:50.747Zmore like thismore than 2014-11-18T15:49:50.747Z
answering member
2000
label Biography information for Earl Howe more like this
tabling member
738
label Biography information for Lord Alton of Liverpool more like this
105776
registered interest false more like this
date less than 2014-11-03more like thismore than 2014-11-03
answering body
Cabinet Office more like this
answering dept id 53 more like this
answering dept short name Cabinet Office more like this
answering dept sort name Cabinet Office more like this
hansard heading Muslim Brotherhood more like this
house id 2 more like this
legislature
25277
pref label House of Lords more like this
question text To ask Her Majesty’s Government when they expect to complete their review of the Muslim Brotherhood; and whether they intend to publish the review’s findings in full. more like this
tabling member printed
Lord Alton of Liverpool more like this
uin HL2590 more like this
answer
answer
is ministerial correction false more like this
date of answer less than 2014-11-10more like thismore than 2014-11-10
answer text <p>I refer the noble Lord to the answer I gave on 13 October 2014, Official Report, Column WA13.</p><p> </p> more like this
answering member printed Lord Wallace of Saltaire more like this
grouped question UIN
HL2591 more like this
HL2592 more like this
question first answered
less than 2014-11-10T18:04:48.5202247Zmore like thismore than 2014-11-10T18:04:48.5202247Z
answering member
1816
label Biography information for Lord Wallace of Saltaire more like this
tabling member
738
label Biography information for Lord Alton of Liverpool more like this
105777
registered interest false more like this
date less than 2014-11-03more like thismore than 2014-11-03
answering body
Cabinet Office more like this
answering dept id 53 more like this
answering dept short name Cabinet Office more like this
answering dept sort name Cabinet Office more like this
hansard heading Muslim Brotherhood more like this
house id 2 more like this
legislature
25277
pref label House of Lords more like this
question text To ask Her Majesty’s Government whether a full list of organisations investigated by their review of the Muslim Brotherhood will be made public, together with any recommended actions. more like this
tabling member printed
Lord Alton of Liverpool more like this
uin HL2591 more like this
answer
answer
is ministerial correction false more like this
date of answer less than 2014-11-10more like thismore than 2014-11-10
answer text <p>I refer the noble Lord to the answer I gave on 13 October 2014, Official Report, Column WA13.</p><p> </p> more like this
answering member printed Lord Wallace of Saltaire more like this
grouped question UIN
HL2590 more like this
HL2592 more like this
question first answered
less than 2014-11-10T18:04:49.8327601Zmore like thismore than 2014-11-10T18:04:49.8327601Z
answering member
1816
label Biography information for Lord Wallace of Saltaire more like this
tabling member
738
label Biography information for Lord Alton of Liverpool more like this
105779
registered interest false more like this
date less than 2014-11-03more like thismore than 2014-11-03
answering body
Cabinet Office more like this
answering dept id 53 more like this
answering dept short name Cabinet Office more like this
answering dept sort name Cabinet Office more like this
hansard heading Muslim Brotherhood more like this
house id 2 more like this
legislature
25277
pref label House of Lords more like this
question text To ask Her Majesty’s Government whether the Cordoba Foundation, Middle East Eye, British Muslim Initiative and Interpal have featured in their review of the Muslim Brotherhood. more like this
tabling member printed
Lord Alton of Liverpool more like this
uin HL2592 more like this
answer
answer
is ministerial correction false more like this
date of answer less than 2014-11-10more like thismore than 2014-11-10
answer text <p>I refer the noble Lord to the answer I gave on 13 October 2014, Official Report, Column WA13.</p><p> </p> more like this
answering member printed Lord Wallace of Saltaire more like this
grouped question UIN
HL2590 more like this
HL2591 more like this
question first answered
less than 2014-11-10T18:04:49.9421012Zmore like thismore than 2014-11-10T18:04:49.9421012Z
answering member
1816
label Biography information for Lord Wallace of Saltaire more like this
tabling member
738
label Biography information for Lord Alton of Liverpool more like this