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<p>The product information refers to irreversible neuropathic conditions, which are
conditions affecting the nervous system.</p><p>The product information states that
neuropsychiatric adverse reactions, such as mood disturbances, psychosis and vestibular
disorders, may occur during treatment and includes warnings and precautions to minimise
these risks. Some of these reactions may persist, but it has not been established
whether these are permanent.</p><p>Mefloquine is effective in the prevention and treatment
of malaria and is approved by the Medicines and Health products Regulatory Agency
(MHRA), which regulates medication in the United Kingdom. As with all medicines, the
MHRA keeps the safety of mefloquine under continual review. Mefloquine continues to
be recommended as a safe and effective form of malaria prevention by the Advisory
Committee on Malaria Prevention, the World Health Organization and other respected
organisations who take account of the body of global evidence.</p><p> </p>
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