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<p>The drug cost to the National Health Service for a one year supply of Apomorphine
for a patient with Parkinson's Disease is estimated to be in the region of £5,300
and £9,000, based on the usual daily dose of 3 – 30mg. However, the maximum daily
is 100mg, so the annual cost for some patient’s treatment may be higher.</p><p>We
have no estimate of the cost of manufacture. We are not aware of any particular issues
relating to the manufacture of this drug. Pharmaceutical companies participate in
either the voluntary pharmaceutical price regulation scheme (PPRS) or the statutory
medicines price regulation scheme, both of which regulate the cost of medicines to
the NHS. Products covered by the statutory scheme are subject to a 15% cut to their
list price. Companies in the PPRS pay a percentage of sales to the Government when
growth in NHS spending on medicines exceeds an agreed level. NHS purchasers may also
negotiate discounts with pharmaceutical companies in addition to national price regulation.</p><p>
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