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1702315

registered interest
date	18/04/2024
answering body	Department of Health and Social Care
answering dept id	17
answering dept short name	Health and Social Care
answering dept sort name	Health and Social Care
hansard heading	Antibiotics
house id	2
legislature	25277 pref label House of Lords
question text	To ask His Majesty's Government what assessment they have made of the report Antibiotic underdosing and disposal in NHS organisations across Great Britain, published in November 2023; and what discussions they have had with the Care Quality Commission on integrating line flushing policies and practices into the assessment framework for care provided in England.
tabling member printed	Baroness Bennett of Manor Castle
uin	HL3926
answer	answer is ministerial correction date of answer 01/05/2024 answer text <p>Officials are aware of, and have considered, the findings of the report Antibiotic underdosing and disposal in NHS organisations across Great Britain. Officials from the Department have not had any recent discussions with the Care Quality Commission on integrating line flushing policies and practices into the assessment framework for care provided in England.</p><p> </p><p>General guidance on prescribing and the use of medicines is published by the National Institute for Health and Care Excellence in an online-only format. Good clinical practice is to flush an intravenous line with saline after a medicine has been administered, to ensure the full dose is delivered to the patient. This is not unique to antibiotics.</p> answering member printed Lord Markham question first answered 01/05/2024 11:05:34 answering member 4948 label Biography information for Lord Markham
tabling member	4719 label Biography information for Baroness Bennett of Manor Castle

1700424

registered interest
date	12/04/2024
answering body	Department of Health and Social Care
answering dept id	17
answering dept short name	Health and Social Care
answering dept sort name	Health and Social Care
hansard heading	Antibiotics
house id	1
legislature	25259 pref label House of Commons
question text	To ask the Secretary of State for Health and Social Care, whether officials in her Department have had recent discussions with the Care Quality Commission on antibiotic underdosing.
tabling member constituency	Putney
tabling member printed	Fleur Anderson
uin	21311
answer	answer is ministerial correction date of answer 17/04/2024 answer text <p>Officials from the Department have not had any recent discussions with the Care Quality Commission on antibiotic underdosing. General guidance on prescribing and the use of medicines is published online by the National Institute for Health and Care Excellence, and is available at the following link:</p><p><a href="https://bnf.nice.org.uk/" target="_blank">https://bnf.nice.org.uk/</a></p> answering member constituency Lewes answering member printed Maria Caulfield question first answered 17/04/2024 09:01:44 answering member 4492 label Biography information for Maria Caulfield
tabling member	4788 label Biography information for Fleur Anderson

1700425

registered interest
date	12/04/2024
answering body	Department of Health and Social Care
answering dept id	17
answering dept short name	Health and Social Care
answering dept sort name	Health and Social Care
hansard heading	Antibiotics
house id	1
legislature	25259 pref label House of Commons
question text	To ask the Secretary of State for Health and Social Care, whether her Department has had discussions with stakeholders on antibiotic line flushing.
tabling member constituency	Putney
tabling member printed	Fleur Anderson
uin	21312
answer	answer is ministerial correction date of answer 17/04/2024 answer text <p>Officials from the Department have not had any recent discussions with stakeholders on antibiotic line flushing. Good clinical practice is to flush an intravenous line with saline after a medicine has been administered, to ensure the full dose is delivered to the patient. This is not unique to antibiotics.</p> answering member constituency Lewes answering member printed Maria Caulfield question first answered 17/04/2024 09:02:57 answering member 4492 label Biography information for Maria Caulfield
tabling member	4788 label Biography information for Fleur Anderson

1692899

registered interest
date	29/02/2024
answering body	Department of Health and Social Care
answering dept id	17
answering dept short name	Health and Social Care
answering dept sort name	Health and Social Care
hansard heading	Antibiotics
house id	2
legislature	25277 pref label House of Lords
question text	To ask His Majesty's Government what assessment they have made of the case for reviewing the expiry dates of antibiotics, including in respect of savings for public expenditure.
tabling member printed	Lord Campbell-Savours
uin	HL2881
answer	answer is ministerial correction date of answer 06/03/2024 answer text <p>The Medicines and Healthcare products Regulatory Agency (MHRA), the Government agency responsible for ensuring that medicines and medical devices work and are acceptably safe, has not made an assessment on the case for reviewing the expiry dates of antibiotics.</p><p>Medicine expiry dates, including for antibiotics, are necessary to ensure that the safety and effectiveness of a medicine is maintained over its long-term shelf life. The active ingredient in many medicines can degrade over time resulting in a loss of potency or the formation of impurities in the product. Physical changes to a medicine such as discolouration, may also occur upon prolonged storage. Medicine expiry dates are supported by stability studies completed by the pharmaceutical company, which demonstrate that a medicine remains safe and effective throughout its shelf life. Any change to the expiry date of a medicine requires an independent review of the stability data by the MHRA.</p><p>Companies can and often do extend the shelf life of their medicines once the product is on the market, and as additional stability data become available. It is not possible, however, to extend the expiry date of all medicines unilaterally in the absence of supporting stability data.</p> answering member printed Lord Markham question first answered 06/03/2024 12:53:44 answering member 4948 label Biography information for Lord Markham
tabling member	499 label Biography information for Lord Campbell-Savours

1667521

registered interest
date	07/11/2023
answering body	Department of Health and Social Care
answering dept id	17
answering dept short name	Health and Social Care
answering dept sort name	Health and Social Care
hansard heading	Antibiotics
house id	1
legislature	25259 pref label House of Commons
question text	To ask the Secretary of State for Health and Social Care, whether he plans to take steps to make (a) Cefiderocol and (b) Ceftazidimethose available on the NHS.
tabling member constituency	Strangford
tabling member printed	Jim Shannon
uin	220
answer	answer is ministerial correction date of answer 09/11/2023 answer text <p>The National Institute for Health and Care Excellence (NICE) is the independent body responsible for developing evidence-based guidance for the National Health Service on whether new medicines represent a clinically and cost-effective use of resources. NICE published guidance in August 2022 recommending both ceftazidime with avibactam and cefiderocol for treating severe drug-resistant gram-negative bacterial infections. This was as part of a project to test a new health technology evaluation process and payment model for antimicrobial products. NHS England has now issued contracts with the suppliers and cefiderocol and ceftazidime with avibactamare available for clinicians to prescribe in line with NICE’s recommendations.</p> answering member constituency Colchester answering member printed Will Quince question first answered 09/11/2023 17:51:11 answering member 4423 label Biography information for Will Quince
tabling member	4131 label Biography information for Jim Shannon

1625772

registered interest
date	03/05/2023
answering body	Department of Health and Social Care
answering dept id	17
answering dept short name	Health and Social Care
answering dept sort name	Health and Social Care
hansard heading	Antibiotics
house id	1
legislature	25259 pref label House of Commons
question text	To ask the Secretary of State for Health and Social Care, what plans his Department has for providing gender or sex-disaggregated data on antibiotic consumption in England.
tabling member constituency	Putney
tabling member printed	Fleur Anderson
uin	183834
answer	answer is ministerial correction date of answer 10/05/2023 answer text <p>The UK Health Security Agency (UKHSA) English surveillance programme for antimicrobial utilisation and resistance report and programme aim to develop and maintain robust surveillance systems for monitoring and reporting trends in antimicrobial use and resistance.</p><p>Alongside surveillance of antibiotic consumptions trends, the report presents evidence pooled from a literature scoping review investigating the association between elements of health inequalities and risk of antimicrobial prescribing in High Income Countries. Trends were identified for sex, with females having the highest overall antibiotic use except for indications including acne, respiratory tract infections and pharyngitis, amongst others.</p><p>The report also presents data on the rate of COVID-19 therapeutics across the country by sex and age. Antibiotic prescribing surveillance data are shared with NHS England and at cross-Government boards on a quarterly basis, as well as being published on the Fingertips tool. UKHSA are committed to identifying surveillance reporting gaps to understand the impact of antimicrobial prescribing and resistance by sex, and on Core20PLUS populations.</p> answering member constituency Lewes answering member printed Maria Caulfield question first answered 10/05/2023 08:14:32 answering member 4492 label Biography information for Maria Caulfield
tabling member	4788 label Biography information for Fleur Anderson

1604132

registered interest
date	14/03/2023
answering body	Department of Health and Social Care
answering dept id	17
answering dept short name	Health and Social Care
answering dept sort name	Health and Social Care
hansard heading	Antibiotics
house id	1
legislature	25259 pref label House of Commons
question text	To ask the Secretary of State for Health and Social Care, whether he has made an assessment of the potential impact of hoarding in the global manufacturing supply chain of antibiotics on the prices of antibiotics in the UK.
tabling member constituency	South Holland and The Deepings
tabling member printed	Sir John Hayes
uin	165203
answer	answer is ministerial correction date of answer 21/03/2023 answer text <p>No assessment has been made. Since 2019, the Government has restricted the export and hoarding of some medicines already placed on the United Kingdom market where there is evidence of a critical shortage, or a risk of a critical shortage, which could adversely impact UK patients.</p><p>For unbranded generic medicines the Department relies on competition to keep prices down. This has led to some of the lowest prices in Europe and allows prices to react to the market. In an international market this ensures that when demand is high and supply is low, prices in the UK can increase to help secure the availability of medicines for UK patients. Branded medicines spend is controlled through the Branded Health Service Medicines (Costs) Regulations 2018 and the 2019 voluntary scheme for branded medicines pricing and access.</p><p>In the UK, anti-competitive behaviour, including hoarding, is a matter for the Competition and Markets Authority (CMA). The Department asks the CMA to investigate where it has concerns about abuses of competition law for generic medicines and where companies are found by the CMA to be in breach of the legislation, the Department will seek damages and invest that money back into the National Health Service.</p> answering member constituency Colchester answering member printed Will Quince question first answered 21/03/2023 17:00:39 answering member 4423 label Biography information for Will Quince
tabling member	350 label Biography information for Sir John Hayes

1564437

registered interest
date	06/01/2023
answering body	Department of Health and Social Care
answering dept id	17
answering dept short name	Health and Social Care
answering dept sort name	Health and Social Care
hansard heading	Antibiotics
house id	1
legislature	25259 pref label House of Commons
question text	To ask the Secretary of State for Health and Social Care, what steps he is taking to help reduce the cost of the charge to the NHS for antibiotics.
tabling member constituency	Warley
tabling member printed	John Spellar
uin	117449
answer	answer is ministerial correction date of answer 13/01/2023 answer text <p>The Government relies on competition to drive down prices of generic medicines such as antibiotics. This has led to some of the lowest prices in Europe. Freedom of pricing enables supplies to put prices up quickly to ensure we maintain continuity of supply despite increasing prices within the global market. In secondary care, tendering for antibiotics on a frequent basis ensures best value and supply resilience is optimised.</p><p>No supplier should use the current situation as an opportunity to exploit the National Health Service. Where companies are found to be abusing their dominant position by charging excessive and unfair prices, the Competition and Markets Authority (CMA) can take action against businesses and individuals engaged in anti-competitive conduct. The CMA is working to establish the facts of what is currently happening in the antibiotic market. They stand ready to take action if there is evidence of anti-competitive behaviour that breaks the law.</p> answering member constituency Colchester answering member printed Will Quince question first answered 13/01/2023 13:26:35 answering member 4423 label Biography information for Will Quince
tabling member	318 label Biography information for John Spellar

1524723

registered interest
date	20/10/2022
answering body	Department of Health and Social Care
answering dept id	17
answering dept short name	Health and Social Care
answering dept sort name	Health and Social Care
hansard heading	Antibiotics
house id	1
legislature	25259 pref label House of Commons
question text	To ask the Secretary of State for Health and Social Care, if she will make an assessment of the (a) dangers and (b) legality of sharing antibiotics; and if she will make a statement.
tabling member constituency	Warrington North
tabling member printed	Charlotte Nichols
uin	68018
answer	answer is ministerial correction date of answer 03/11/2022 answer text <p>All use of antimicrobials can drive resistance, so they should only be used when necessary. The Government supports various initiatives to strengthen the stewardship and support the appropriate use of antimicrobials. Sharing prescription medications, including antibiotics, is against the law.</p> answering member constituency Colchester answering member printed Will Quince question first answered 03/11/2022 13:12:54 answering member 4423 label Biography information for Will Quince
tabling member	4799 label Biography information for Charlotte Nichols

1255620

registered interest
date	25/11/2020
answering body	Department of Health and Social Care
answering dept id	17
answering dept short name	Health and Social Care
answering dept sort name	Health and Social Care
hansard heading	Antibiotics
house id	2
legislature	25277 pref label House of Lords
question text	To ask Her Majesty's Government what plans they have (1) to encourage, (2) to support, and (3) to enforce, the use of antibiotic consumption data as a public health measure in decisions about (a) trade policy, and (b) the protection of public health.
tabling member printed	Baroness Bennett of Manor Castle
uin	HL10691
answer	answer is ministerial correction date of answer 04/12/2020 answer text <p>Public health issues are being actively considered as part of the Government’s trade policy development. The Government has been clear that it will uphold the United Kingdom’s high levels of public, animal, and plant health.</p><p>The UK’s five-year national action plan for antimicrobial resistance includes ambitions to reduce antimicrobial use in human and animal medicine. Public Health England (PHE) works with the National Health Service to develop and maintain robust surveillance systems for monitoring and reporting trends in antimicrobial use. Local data on antibiotic prescribing is published by PHE in an online only format and can be used by healthcare staff, commissioners and directors of public health to benchmark performance and develop local action plans.</p> answering member printed Lord Bethell question first answered 04/12/2020 14:41:11 answering member 4708 label Biography information for Lord Bethell
tabling member	4719 label Biography information for Baroness Bennett of Manor Castle