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172719

registered interest
date	08/01/2015
answering body	Home Office
answering dept id	1
answering dept short name	Home Office
answering dept sort name	Home Office
hansard heading	Government Departments: Staff
house id	2
legislature	25277 pref label House of Lords
question text	To ask Her Majesty’s Government, further to the Written Answers by Lord Bates on 18 December 2014 (HL3693) and by Lord Henley on 13 March 2013 (WA 73) and 10 January 2012 (WA37–8), which Home Office Minister authorised the decision to withhold from Parliament the names of the Home Office officials convicted of offences relating to misconduct in public office for which they have received custodial sentences; and when the previous practice of revealing such names in parliamentary answers was changed.
tabling member printed	Lord Marlesford
uin	HL4039
answer	answer is ministerial correction date of answer 12/02/2015 answer text <p>Lord Bates approved the response to HL3693 but in view of the Noble Lords further question we are reviewing our position and will write accordingly.</p><p> </p> answering member printed Lord Bates question first answered 12/02/2015 17:42:01 answering member 1091 label Biography information for Lord Bates
tabling member	1854 label Biography information for Lord Marlesford

172721

registered interest
date	08/01/2015
answering body	Department for Environment, Food and Rural Affairs
answering dept id	13
answering dept short name	Environment, Food and Rural Affairs
answering dept sort name	Environment, Food and Rural Affairs
hansard heading	Motor Vehicles: Litter
house id	2
legislature	25277 pref label House of Lords
question text	To ask Her Majesty’s Government whether they have invited tenders for the scoping study to obtain the evidence on which to base regulations on littering from vehicles as required by the Anti-social Behaviour, Crime and Policing Act 2014; and when they expect the study to be completed.
tabling member printed	Lord Marlesford
uin	HL4041
answer	answer is ministerial correction date of answer 19/01/2015 answer text <p>Defra invited tenders for the scoping study on 10 December last year. The study is expected to be completed by the end of March this year.</p><p> </p> answering member printed Lord De Mauley question first answered 19/01/2015 15:37:27 answering member 2202 label Biography information for Lord De Mauley
tabling member	1854 label Biography information for Lord Marlesford

172722

registered interest
date	08/01/2015
answering body	Department of Health
answering dept id	17
answering dept short name	Health
answering dept sort name	Health
hansard heading	IVF
house id	2
legislature	25277 pref label House of Lords
question text	To ask Her Majesty’s Government, further to the Written Answer by Earl Howe on 6 February 2014 (WA 76) and the Written Statement by the Parliamentary Under-Secretary of State for Public Health, Jane Ellison, on 17 December 2014 (HC Deb, cols 96–7WS), whether an enucleated embryo being unable to survive without nuclear DNA necessarily implies that both steps of the different processes described in Regulations 4 and 7 must be completed in their entirety in order to generate the permitted egg or embryo referred to in Regulations 3(a) and 6(a) respectively of the Draft Human Fertilisation and Embryology (Mitochondrial Donation) Regulations 2015; and if not, whether they will describe how individual eggs or embryos that have been enucleated might be used directly in infertility treatment as egg P or embryo P.
tabling member printed	Lord Alton of Liverpool
uin	HL4042
answer	answer is ministerial correction date of answer 22/01/2015 answer text <p>Enucleated eggs and embryos are, in themselves, non-viable and, therefore, cannot be used for the treatment of infertility. The different processes used to generate a permitted egg or embryo, referred to in Regulations 4 and 7, will be completed in their entirety.</p><p> </p> answering member printed Earl Howe question first answered 22/01/2015 11:50:59 answering member 2000 label Biography information for Earl Howe
tabling member	738 label Biography information for Lord Alton of Liverpool

172723

registered interest
date	08/01/2015
answering body	Department of Health
answering dept id	17
answering dept short name	Health
answering dept sort name	Health
hansard heading	IVF
house id	2
legislature	25277 pref label House of Lords
question text	To ask Her Majesty’s Government, further to the Written Statement by the Parliamentary Under-Secretary of State for Public Health, Jane Ellison, on 17 December 2014 (HC Deb, col. 96WS), what concerns were raised by the expert panel convened by the Human Fertilisation and Embryology Authority (HFEA) regarding the possibility of carryover of a small percentage of abnormal mitochondrial DNA (mtDNA) from the affected oocyte or zygote as a result of close associations between mtDNA and the karyoplast; what additional consideration the HFEA’s expert panel gave to replicative advantage of some mtDNA variants skewing the proportions in subsequent development as a result of a mitochondrial bottleneck; whether they can therefore guarantee that no females born following spindle-chromosomal complex transfer or pronuclear transfer would ever transmit the disease to subsequent generations; if not, whether serial nuclear transfer would minimise this risk; and why serial nuclear transfer is precluded by Regulations 3(c) and 6(c) of the Draft Human Fertilisation and Embryology (Mitochondrial Donation) Regulations 2015, which prevent any further "alterations in the nuclear or mitochondrial DNA".
tabling member printed	Lord Alton of Liverpool
uin	HL4043
answer	answer is ministerial correction date of answer 22/01/2015 answer text <p>We are advised by the Human Fertilisation and Embryology Authority (HFEA) that the issues raised by the noble Lord are discussed at various points in the Expert Panel’s 2014 report, as follows:</p><p> </p><p> </p><p> </p><p>- mitochondrial DNA carryover at sections 3.7.2 to 3.7.11;</p><p> </p><p>- nuclear-mitochondrial interactions at sections 3.7.15 to 3.7.20; and</p><p> </p><p>- points relating to replicative advantage and mitochondrial bottleneck are widely discussed throughout section 3.</p><p> </p><p> </p><p> </p><p>The Panel’s report is attached.</p><p> </p><p> </p><p> </p><p>The HFEA has also advised that the Expert Panel it convened concluded that, following Maternal Spindle Transfer or Pronuclear Transfer, the risks of mitochondrial disease in the next generation will be low. Further details can be found in section 3 of the Panel’s 2014 report.</p><p> </p><p> </p><p> </p><p>Serial nuclear transfer is not a term or process connected with mitochondrial donation. Therefore, serial transfer is not something the Expert Panel has considered.</p><p> </p> answering member printed Earl Howe question first answered 22/01/2015 16:49:38 answering member 2000 label Biography information for Earl Howe attachment 1 file name HFEA Panel's Report.pdf title HFEA's Panel Report
tabling member	738 label Biography information for Lord Alton of Liverpool