http://www.hfea.gov.uk/docs/Third_Mitochondrial_replacement_scientific_review.pdf<\/a><\/p> <\/p>
<\/p>
<\/p>
The Expert Panel considered the risk of mismatch between the mitochondrial and nuclear genomes to be very low. Even this extremely low risk could be avoided in mitochondrial donation treatment by matching the patient\u2019s mitochondrial DNA haplogroup to that of the donor. Given that mitochondrial DNA does not affect physical or personal characteristics, and the risk of mito-nuclear mismatch is very low, mitochondrial donation techniques are not considered to have any effect on the characteristics of children born as a result of these techniques.<\/p>
<\/p>"}
, "answeringMember" : {"_about" : "http://data.parliament.uk/members/3918", "label" : {"_value" : "Biography information for Jane Ellison"}
}
, "answeringMemberConstituency" : {"_value" : "Battersea"}
, "answeringMemberPrinted" : {"_value" : "Jane Ellison"}
, "dateOfAnswer" : {"_value" : "2015-02-23", "_datatype" : "dateTime"}
, "isMinisterialCorrection" : {"_value" : "false", "_datatype" : "boolean"}
, "questionFirstAnswered" : [{"_value" : "2015-02-23T16:56:24.523Z", "_datatype" : "dateTime"}
]}
, "answeringDeptId" : {"_value" : "17"}
, "answeringDeptShortName" : {"_value" : "Health"}
, "answeringDeptSortName" : {"_value" : "Health"}
, "date" : {"_value" : "2015-02-11", "_datatype" : "dateTime"}
, "hansardHeading" : {"_value" : "IVF"}
, "houseId" : {"_value" : "1"}
, "legislature" : [{"_about" : "http://data.parliament.uk/terms/25259", "prefLabel" : {"_value" : "House of Commons"}
}
], "questionText" : "To ask the Secretary of State for Health, if he will make an assessment of the implications for his Department's policy on the effects of mitochondrial donation techniques on the characteristics of children born as a result of those techniques of research by (a) Woolf et al, Mitonuclear interactions: evolutionary consequences over multiple biological scales, published in the Philosophical Transactions of the Royal Society B: Biological Sciences 369, 20130443, 2014 and (b) Løvlie, et al, The influence of mitonuclear genetic variation on personality in seed beetles, published in Proceedings of the Royal Society B: Biological Sciences.", "registeredInterest" : {"_value" : "false", "_datatype" : "boolean"}
, "tablingMember" : {"_about" : "http://data.parliament.uk/members/4126", "label" : {"_value" : "Biography information for Mary Glindon"}
}
, "tablingMemberConstituency" : {"_value" : "North Tyneside"}
, "tablingMemberPrinted" : [{"_value" : "Mrs Mary Glindon"}
], "uin" : "224152"}
, {"_about" : "http://data.parliament.uk/resources/178537", "AnsweringBody" : [{"_value" : "Department of Health"}
], "answer" : {"_about" : "http://data.parliament.uk/resources/178537/answer", "answerText" : {"_value" : "
The Human Fertilisation and Embryology (Mitochondrial Donation) Regulations 2015, if approved by Parliament, will not come into force until 29 October 2015.<\/p>
<\/p>
<\/p>
<\/p>
The Human Fertilisation and Embryology Authority (HFEA) will consider how best to apply a monitoring framework to clinics awarded a licence to carry out mitochondrial donation treatment, against which it would inspect. The HFEA will announce its proposals for the regulation and monitoring of mitochondrial donation treatment cycles following the approval of regulations by Parliament.<\/p>
<\/p>"}
, "answeringMember" : {"_about" : "http://data.parliament.uk/members/3918", "label" : {"_value" : "Biography information for Jane Ellison"}
}
, "answeringMemberConstituency" : {"_value" : "Battersea"}
, "answeringMemberPrinted" : {"_value" : "Jane Ellison"}
, "dateOfAnswer" : {"_value" : "2015-02-12", "_datatype" : "dateTime"}
, "isMinisterialCorrection" : {"_value" : "false", "_datatype" : "boolean"}
, "questionFirstAnswered" : [{"_value" : "2015-02-12T17:37:06.057Z", "_datatype" : "dateTime"}
]}
, "answeringDeptId" : {"_value" : "17"}
, "answeringDeptShortName" : {"_value" : "Health"}
, "answeringDeptSortName" : {"_value" : "Health"}
, "date" : {"_value" : "2015-02-09", "_datatype" : "dateTime"}
, "hansardHeading" : {"_value" : "IVF"}
, "houseId" : {"_value" : "1"}
, "legislature" : [{"_about" : "http://data.parliament.uk/terms/25259", "prefLabel" : {"_value" : "House of Commons"}
}
], "questionText" : "To ask the Secretary of State for Health, what steps his Department plans to take to monitor the long-term health and wellbeing of (a) people born following mitochondrial donation who have passed the age of 18 and choose not to remain part of a clinical trial and (b) the descendants of people born following mitochondrial donation.", "registeredInterest" : {"_value" : "false", "_datatype" : "boolean"}
, "tablingMember" : {"_about" : "http://data.parliament.uk/members/4126", "label" : {"_value" : "Biography information for Mary Glindon"}
}
, "tablingMemberConstituency" : {"_value" : "North Tyneside"}
, "tablingMemberPrinted" : [{"_value" : "Mrs Mary Glindon"}
], "uin" : "223867"}
, {"_about" : "http://data.parliament.uk/resources/178544", "AnsweringBody" : [{"_value" : "Department of Health"}
], "answer" : {"_about" : "http://data.parliament.uk/resources/178544/answer", "answerText" : {"_value" : "
The Government\u2019s analysis of estimated costs and benefits is contained in the Impact Assessment that was laid in Parliament, together with the Draft Human Fertilisation and Embryology (Mitochondrial Donation) Regulations 2015, on 17 December 2014.<\/p>
<\/p>
<\/p>
<\/p>
The cost over 10 years was estimated at £11.1 million with the monetised benefit estimated at £329.2 million.<\/p>
<\/p>"}
, "answeringMember" : {"_about" : "http://data.parliament.uk/members/3918", "label" : {"_value" : "Biography information for Jane Ellison"}
}
, "answeringMemberConstituency" : {"_value" : "Battersea"}
, "answeringMemberPrinted" : {"_value" : "Jane Ellison"}
, "dateOfAnswer" : {"_value" : "2015-02-12", "_datatype" : "dateTime"}
, "isMinisterialCorrection" : {"_value" : "false", "_datatype" : "boolean"}
, "questionFirstAnswered" : [{"_value" : "2015-02-12T17:20:11.13Z", "_datatype" : "dateTime"}
]}
, "answeringDeptId" : {"_value" : "17"}
, "answeringDeptShortName" : {"_value" : "Health"}
, "answeringDeptSortName" : {"_value" : "Health"}
, "date" : {"_value" : "2015-02-09", "_datatype" : "dateTime"}
, "hansardHeading" : {"_value" : "Hereditary Diseases"}
, "houseId" : {"_value" : "1"}
, "legislature" : [{"_about" : "http://data.parliament.uk/terms/25259", "prefLabel" : {"_value" : "House of Commons"}
}
], "questionText" : "To ask the Secretary of State for Health, what estimate he has made of the cost to the public purse of (a) treatments for mitochondrial disease involving mitochondrial donation and (b) treatments for mitochondrial disease that do not involve mitochondrial donation in each of the next five financial years.", "registeredInterest" : {"_value" : "false", "_datatype" : "boolean"}
, "tablingMember" : {"_about" : "http://data.parliament.uk/members/4126", "label" : {"_value" : "Biography information for Mary Glindon"}
}
, "tablingMemberConstituency" : {"_value" : "North Tyneside"}
, "tablingMemberPrinted" : [{"_value" : "Mrs Mary Glindon"}
], "uin" : "223866"}
, {"_about" : "http://data.parliament.uk/resources/178612", "AnsweringBody" : [{"_value" : "Department for Work and Pensions"}
], "answer" : {"_about" : "http://data.parliament.uk/resources/178612/answer", "answerText" : {"_value" : "
No information is held about the specific cost incurred by people using the Disability Living Allowance Helpline which can be accessed using an 0345 or 0845 number prefix.<\/p>
<\/p>
DWP is in the process of removing 0845 number prefixes for its national helplines.<\/p>"}
, "answeringMember" : {"_about" : "http://data.parliament.uk/members/1520", "label" : {"_value" : "Biography information for Mr Mark Harper"}
}
, "answeringMemberConstituency" : {"_value" : "Forest of Dean"}
, "answeringMemberPrinted" : {"_value" : "Mr Mark Harper"}
, "dateOfAnswer" : {"_value" : "2015-02-25", "_datatype" : "dateTime"}
, "isMinisterialCorrection" : {"_value" : "false", "_datatype" : "boolean"}
, "questionFirstAnswered" : [{"_value" : "2015-02-25T17:07:27.997Z", "_datatype" : "dateTime"}
]}
, "answeringDeptId" : {"_value" : "29"}
, "answeringDeptShortName" : {"_value" : "Work and Pensions"}
, "answeringDeptSortName" : {"_value" : "Work and Pensions"}
, "date" : {"_value" : "2015-02-09", "_datatype" : "dateTime"}
, "hansardHeading" : {"_value" : "Telephone Services"}
, "houseId" : {"_value" : "1"}
, "legislature" : [{"_about" : "http://data.parliament.uk/terms/25259", "prefLabel" : {"_value" : "House of Commons"}
}
], "questionText" : "To ask the Secretary of State for Work and Pensions, what information his Department holds about costs incurred by people using the Disability Living Allowance helpline; and if he will make a statement.", "registeredInterest" : {"_value" : "false", "_datatype" : "boolean"}
, "tablingMember" : {"_about" : "http://data.parliament.uk/members/4126", "label" : {"_value" : "Biography information for Mary Glindon"}
}
, "tablingMemberConstituency" : {"_value" : "North Tyneside"}
, "tablingMemberPrinted" : [{"_value" : "Mrs Mary Glindon"}
], "uin" : "223824"}
, {"_about" : "http://data.parliament.uk/resources/173498", "AnsweringBody" : [{"_value" : "Department for Work and Pensions"}
], "answer" : {"_about" : "http://data.parliament.uk/resources/173498/answer", "answerText" : {"_value" : "
The total number of Jobseeker\u2019s Allowance (JSA) hardship awards made in each month from April 2011 to March 2012 (the latest available published data) is shown in the table below.<\/p>
<\/p>
Number of hardship awards in each month 2011-12, Great Britain<\/strong><\/p>Month<\/strong><\/p><\/td>No. of awards<\/strong><\/p><\/td><\/tr>Apr-2011<\/strong><\/p><\/td>5,000<\/p><\/td><\/tr> | May-2011<\/strong><\/p><\/td>6,000<\/p><\/td><\/tr> | Jun-2011<\/strong><\/p><\/td>6,000<\/p><\/td><\/tr> | Jul-2011<\/strong><\/p><\/td>5,000<\/p><\/td><\/tr> | Aug-2011<\/strong><\/p><\/td>5,000<\/p><\/td><\/tr> | Sep-2011<\/strong><\/p><\/td>5,000<\/p><\/td><\/tr> | Oct-2011<\/strong><\/p><\/td>5,000<\/p><\/td><\/tr> | Nov-2011<\/strong><\/p><\/td>6,000<\/p><\/td><\/tr> | Dec-2011<\/strong><\/p><\/td>5,000<\/p><\/td><\/tr> | Jan-2012<\/strong><\/p><\/td>5,000<\/p><\/td><\/tr> | Feb-2012<\/strong><\/p><\/td>6,000<\/p><\/td><\/tr> | Mar-2012<\/strong><\/p><\/td>6,000<\/p><\/td><\/tr> | 2011-12 total<\/strong><\/p><\/td>64,000<\/p><\/td><\/tr><\/tbody><\/table> <\/strong><\/p>Notes:<\/p> The numbers of JSA Hardship Awards were collated from aggregate DWP MISP Management Information. This data is a combination of system and clerically sourced Management Information. It is not considered 100% reliable and may contain duplicates. Numbers have been rounded to the nearest 1,000.<\/p> <\/p>"}
, "answeringMember" : {"_about" : "http://data.parliament.uk/members/4084", "label" : {"_value" : "Biography information for Esther McVey"}
}
, "answeringMemberConstituency" : {"_value" : "Wirral West"}
, "answeringMemberPrinted" : {"_value" : "Esther McVey"}
, "dateOfAnswer" : {"_value" : "2015-01-21", "_datatype" : "dateTime"}
, "isMinisterialCorrection" : {"_value" : "false", "_datatype" : "boolean"}
, "previousAnswerVersion" : {"_about" : "http://data.parliament.uk/resources/173498/answer/previousversion/38911", "answeringMember" : {"_about" : "http://data.parliament.uk/members/4084", "label" : {"_value" : "Biography information for Esther McVey"}
}
, "answeringMemberConstituency" : {"_value" : "Wirral West"}
, "answeringMemberPrinted" : {"_value" : "Esther McVey"}
}
, "questionFirstAnswered" : [{"_value" : "2015-01-21T16:15:51.463Z", "_datatype" : "dateTime"}
]}
, "answeringDeptId" : {"_value" : "29"}
, "answeringDeptShortName" : {"_value" : "Work and Pensions"}
, "answeringDeptSortName" : {"_value" : "Work and Pensions"}
, "date" : {"_value" : "2015-01-13", "_datatype" : "dateTime"}
, "hansardHeading" : {"_value" : "Social Security Benefits"}
, "houseId" : {"_value" : "1"}
, "legislature" : [{"_about" : "http://data.parliament.uk/terms/25259", "prefLabel" : {"_value" : "House of Commons"}
}
], "questionText" : "To ask the Secretary of State for Work and Pensions, how many hardship payments were made to sanctioned jobseeker's allowance claimants in each of the last 12 months for which figures are available.", "registeredInterest" : {"_value" : "false", "_datatype" : "boolean"}
, "tablingMember" : {"_about" : "http://data.parliament.uk/members/4126", "label" : {"_value" : "Biography information for Mary Glindon"}
}
, "tablingMemberConstituency" : {"_value" : "North Tyneside"}
, "tablingMemberPrinted" : [{"_value" : "Mrs Mary Glindon"}
], "uin" : "220640"}
, {"_about" : "http://data.parliament.uk/resources/172797", "AnsweringBody" : [{"_value" : "Department of Health"}
], "answer" : {"_about" : "http://data.parliament.uk/resources/172797/answer", "answerText" : {"_value" : " There are already arrangements in place to support children born with conditions relating.<\/p> <\/p>"}
, "answeringMember" : {"_about" : "http://data.parliament.uk/members/3918", "label" : {"_value" : "Biography information for Jane Ellison"}
}
, "answeringMemberConstituency" : {"_value" : "Battersea"}
, "answeringMemberPrinted" : {"_value" : "Jane Ellison"}
, "dateOfAnswer" : {"_value" : "2015-01-13", "_datatype" : "dateTime"}
, "isMinisterialCorrection" : {"_value" : "false", "_datatype" : "boolean"}
, "questionFirstAnswered" : [{"_value" : "2015-01-13T15:16:23.13Z", "_datatype" : "dateTime"}
]}
, "answeringDeptId" : {"_value" : "17"}
, "answeringDeptShortName" : {"_value" : "Health"}
, "answeringDeptSortName" : {"_value" : "Health"}
, "date" : {"_value" : "2015-01-08", "_datatype" : "dateTime"}
, "hansardHeading" : {"_value" : "IVF"}
, "houseId" : {"_value" : "1"}
, "legislature" : [{"_about" : "http://data.parliament.uk/terms/25259", "prefLabel" : {"_value" : "House of Commons"}
}
], "questionText" : "To ask the Secretary of State for Health, whether he plans to put contingency arrangements in place to ensure support for recipients of mitochondrial donation techniques in the event of failure or abnormal development in the resulting child.", "registeredInterest" : {"_value" : "false", "_datatype" : "boolean"}
, "tablingMember" : {"_about" : "http://data.parliament.uk/members/4126", "label" : {"_value" : "Biography information for Mary Glindon"}
}
, "tablingMemberConstituency" : {"_value" : "North Tyneside"}
, "tablingMemberPrinted" : [{"_value" : "Mrs Mary Glindon"}
], "uin" : "220183"}
, {"_about" : "http://data.parliament.uk/resources/172798", "AnsweringBody" : [{"_value" : "Department of Health"}
], "answer" : {"_about" : "http://data.parliament.uk/resources/172798/answer", "answerText" : {"_value" : " Neither the nuclear DNA or mitochondrial DNA of the patient\u2019s egg is altered during the creation of an embryo during mitochondrial donation treatment, using the maternal spindle transfer (MST) and pro-nuclear transfer (PNT) techniques.<\/p> <\/p>"}
, "answeringMember" : {"_about" : "http://data.parliament.uk/members/3918", "label" : {"_value" : "Biography information for Jane Ellison"}
}
, "answeringMemberConstituency" : {"_value" : "Battersea"}
, "answeringMemberPrinted" : {"_value" : "Jane Ellison"}
, "dateOfAnswer" : {"_value" : "2015-01-13", "_datatype" : "dateTime"}
, "isMinisterialCorrection" : {"_value" : "false", "_datatype" : "boolean"}
, "questionFirstAnswered" : [{"_value" : "2015-01-13T15:21:06.287Z", "_datatype" : "dateTime"}
]}
, "answeringDeptId" : {"_value" : "17"}
, "answeringDeptShortName" : {"_value" : "Health"}
, "answeringDeptSortName" : {"_value" : "Health"}
, "date" : {"_value" : "2015-01-08", "_datatype" : "dateTime"}
, "hansardHeading" : {"_value" : "IVF"}
, "houseId" : {"_value" : "1"}
, "legislature" : [{"_about" : "http://data.parliament.uk/terms/25259", "prefLabel" : {"_value" : "House of Commons"}
}
], "questionText" : "To ask the Secretary of State for Health, what assessment his Department has made of whether eggs used in the creation of embryos through maternal spindle transfer or pronuclear transfer have had their mitochondrial or nuclear genes altered in the process.", "registeredInterest" : {"_value" : "false", "_datatype" : "boolean"}
, "tablingMember" : {"_about" : "http://data.parliament.uk/members/4126", "label" : {"_value" : "Biography information for Mary Glindon"}
}
, "tablingMemberConstituency" : {"_value" : "North Tyneside"}
, "tablingMemberPrinted" : [{"_value" : "Mrs Mary Glindon"}
], "uin" : "220181"}
, {"_about" : "http://data.parliament.uk/resources/172799", "AnsweringBody" : [{"_value" : "Department of Health"}
], "answer" : {"_about" : "http://data.parliament.uk/resources/172799/answer", "answerText" : {"_value" : " I refer the hon. Member to the answer given to the hon. Member for Congleton (Fiona Bruce) on 3 December 2014 to Question 216104<\/a>.<\/p> <\/p> <\/p> <\/p>"}
, "answeringMember" : {"_about" : "http://data.parliament.uk/members/3918", "label" : {"_value" : "Biography information for Jane Ellison"}
}
, "answeringMemberConstituency" : {"_value" : "Battersea"}
, "answeringMemberPrinted" : {"_value" : "Jane Ellison"}
, "dateOfAnswer" : {"_value" : "2015-01-13", "_datatype" : "dateTime"}
, "isMinisterialCorrection" : {"_value" : "false", "_datatype" : "boolean"}
, "questionFirstAnswered" : [{"_value" : "2015-01-13T16:17:02.577Z", "_datatype" : "dateTime"}
]}
, "answeringDeptId" : {"_value" : "17"}
, "answeringDeptShortName" : {"_value" : "Health"}
, "answeringDeptSortName" : {"_value" : "Health"}
, "date" : {"_value" : "2015-01-08", "_datatype" : "dateTime"}
, "hansardHeading" : {"_value" : "IVF"}
, "houseId" : {"_value" : "1"}
, "legislature" : [{"_about" : "http://data.parliament.uk/terms/25259", "prefLabel" : {"_value" : "House of Commons"}
}
], "questionText" : "To ask the Secretary of State for Health, what assessment he has made of the implications for public safety in relation to his policy on mitochondrial transfer of the study by Professor John Zhang et al, published in Fertility and Sterility, Vol 80, Suppl. 3, September 2003.", "registeredInterest" : {"_value" : "false", "_datatype" : "boolean"}
, "tablingMember" : {"_about" : "http://data.parliament.uk/members/4126", "label" : {"_value" : "Biography information for Mary Glindon"}
}
, "tablingMemberConstituency" : {"_value" : "North Tyneside"}
, "tablingMemberPrinted" : [{"_value" : "Mrs Mary Glindon"}
], "uin" : "220182"}
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}
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