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A recent study demonstrated a two-dose vaccine efficacy of 95% for the Pfizer/Biotech COVID-19 vaccine, with a second dose delivered between 19 and 42 days. The Joint Committee on Vaccination and Immunisation (JCVI) has reviewed evidence on the Pfizer/BioNTech COVID-19 vaccine and advised an interval of up to 12 weeks between doses. The considerations of the JCVI on extended intervals has been published, and is available here: https://www.gov.uk/government/publications/prioritising-the-first-covid-19-vaccine-dose-jcvi-statement<\/a><\/p>

Using data available from clinical trials, Public Health England estimated that vaccine efficacy from the first dose of the Pfizer/BioNTech vaccine is approximately 89%. This is the efficacy calculated 15 to 21 days after the first dose. The estimate for 15 to 28 days is 91% which includes seven days after the second dose, but is prior to the time protection that may be expected from the second dose. There is no estimate of efficacy for a single dose beyond 21 days, but the JCVI\u2019s view is that protective immunity from the first dose likely lasts for a duration of 12 weeks.<\/p>"} , "answeringMember" : {"_about" : "http://data.parliament.uk/members/4113", "label" : {"_value" : "Biography information for Nadhim Zahawi"} } , "answeringMemberConstituency" : {"_value" : "Stratford-on-Avon"} , "answeringMemberPrinted" : {"_value" : "Nadhim Zahawi"} , "dateOfAnswer" : {"_value" : "2021-01-18", "_datatype" : "dateTime"} , "groupedQuestionUIN" : [{"_value" : "134548"} , {"_value" : "134549"} ], "isMinisterialCorrection" : {"_value" : "false", "_datatype" : "boolean"} , "previousAnswerVersion" : {"_about" : "http://data.parliament.uk/resources/1274717/answer/previousversion/73470", "answeringMember" : {"_about" : "http://data.parliament.uk/members/4113", "label" : {"_value" : "Biography information for Nadhim Zahawi"} } , "answeringMemberConstituency" : {"_value" : "Stratford-on-Avon"} , "answeringMemberPrinted" : {"_value" : "Nadhim Zahawi"} } , "questionFirstAnswered" : [{"_value" : "2021-01-18T11:48:46.017Z", "_datatype" : "dateTime"} ]} , "answeringDeptId" : {"_value" : "17"} , "answeringDeptShortName" : {"_value" : "Health and Social Care"} , "answeringDeptSortName" : {"_value" : "Health and Social Care"} , "date" : {"_value" : "2021-01-08", "_datatype" : "dateTime"} , "hansardHeading" : {"_value" : "Coronavirus: Vaccination"} , "houseId" : {"_value" : "1"} , "legislature" : [{"_about" : "http://data.parliament.uk/terms/25259", "prefLabel" : {"_value" : "House of Commons"} } ], "questionText" : "To ask the Secretary of State for Health and Social Care, what assessment his Department has made of the effectiveness of the Pfizer/BioNTech covid-19 vaccine if the second dose is administered 12 weeks after the first dose.", "registeredInterest" : {"_value" : "false", "_datatype" : "boolean"} , "tablingMember" : {"_about" : "http://data.parliament.uk/members/4671", "label" : {"_value" : "Biography information for Afzal Khan"} } , "tablingMemberConstituency" : {"_value" : "Manchester, Gorton"} , "tablingMemberPrinted" : [{"_value" : "Afzal Khan"} ], "uin" : "134547"} ], "itemsPerPage" : 10, "page" : 0, "startIndex" : 1, "totalResults" : 1, "type" : ["http://purl.org/linked-data/api/vocab#ListEndpoint", "http://purl.org/linked-data/api/vocab#Page"]} }