The 100,000 Genome Project was subject to a final review in July 2019 by the Infrastructure and Projects Authority (IPA). The IPA rated the 100,000 Genomes Project Gateway 5 as Green and found that the Project has \u201csuccessfully delivered against its key aims and to the revised time scale, cost and quality\u201d.<\/p>"} , "answeringMember" : {"_about" : "http://data.parliament.uk/members/4909", "label" : {"_value" : "Biography information for Lord Kamall"} } , "answeringMemberPrinted" : {"_value" : "Lord Kamall"} , "dateOfAnswer" : {"_value" : "2021-11-26", "_datatype" : "dateTime"} , "isMinisterialCorrection" : {"_value" : "false", "_datatype" : "boolean"} , "questionFirstAnswered" : [{"_value" : "2021-11-26T13:44:11.233Z", "_datatype" : "dateTime"} ]} , "answeringDeptId" : {"_value" : "17"} , "answeringDeptShortName" : {"_value" : "Health and Social Care"} , "answeringDeptSortName" : {"_value" : "Health and Social Care"} , "date" : {"_value" : "2021-11-15", "_datatype" : "dateTime"} , "hansardHeading" : {"_value" : "100,000 Genomes Project"} , "houseId" : {"_value" : "2"} , "legislature" : [{"_about" : "http://data.parliament.uk/terms/25277", "prefLabel" : {"_value" : "House of Lords"} } ], "questionText" : "To ask Her Majesty's Government what assessment they have made of the 100,000 Genomes Project.", "registeredInterest" : {"_value" : "false", "_datatype" : "boolean"} , "tablingMember" : {"_about" : "http://data.parliament.uk/members/4130", "label" : {"_value" : "Biography information for Baroness Ritchie of Downpatrick"} } , "tablingMemberPrinted" : [{"_value" : "Baroness Ritchie of Downpatrick"} ], "uin" : "HL4029"} , {"_about" : "http://data.parliament.uk/resources/1135751", "AnsweringBody" : [{"_value" : "Department of Health and Social Care"} ], "answer" : {"_about" : "http://data.parliament.uk/resources/1135751/answer", "answerText" : {"_value" : "
Genomics England is committed to returning results to every patient in the 100,000 Genomes Project via their National Health Service clinical team. All of the patient results will have been returned to the NHS by the end of the year.<\/p>
Under the Data Protection Legislation, participants in the 100,000 Genomes Project can request their genomic and clinical data. However, a whole genome sequence is around 3 billion letters long and written in code so it is very difficult to interpret. Genomics England can provide access to a visual representation on request or provide access to the raw data. A NHS clinical team is the best route to providing a clinical interpretation of the genome results.<\/p>"} , "answeringMember" : {"_about" : "http://data.parliament.uk/members/4019", "label" : {"_value" : "Biography information for Baroness Blackwood of North Oxford"} } , "answeringMemberPrinted" : {"_value" : "Baroness Blackwood of North Oxford"} , "dateOfAnswer" : {"_value" : "2019-07-10", "_datatype" : "dateTime"} , "isMinisterialCorrection" : {"_value" : "false", "_datatype" : "boolean"} , "questionFirstAnswered" : [{"_value" : "2019-07-10T15:26:14.307Z", "_datatype" : "dateTime"} ]} , "answeringDeptId" : {"_value" : "17"} , "answeringDeptShortName" : {"_value" : "Health and Social Care"} , "answeringDeptSortName" : {"_value" : "Health and Social Care"} , "date" : {"_value" : "2019-07-01", "_datatype" : "dateTime"} , "hansardHeading" : {"_value" : "100,000 Genomes Project"} , "houseId" : {"_value" : "2"} , "legislature" : [{"_about" : "http://data.parliament.uk/terms/25277", "prefLabel" : {"_value" : "House of Lords"} } ], "questionText" : "To ask Her Majesty's Government whether those who have taken part in the NHS 100,000 Genome Project are being denied access to their own genome data; and if so, why.", "registeredInterest" : {"_value" : "false", "_datatype" : "boolean"} , "tablingMember" : {"_about" : "http://data.parliament.uk/members/4333", "label" : {"_value" : "Biography information for Lord Scriven"} } , "tablingMemberPrinted" : [{"_value" : "Lord Scriven"} ], "uin" : "HL16844"} , {"_about" : "http://data.parliament.uk/resources/1134907", "AnsweringBody" : [{"_value" : "Department of Health and Social Care"} ], "answer" : {"_about" : "http://data.parliament.uk/resources/1134907/answer", "answerText" : {"_value" : "
As a Government Major Project, the 100,000 Genomes Project has been under regular review by the Infrastructure and Projects Authority (IPA) which provides independent assurance of the most complex and strategically significant projects across Government. As part of this, the 100,000 Genomes Project has undergone several significant reviews which considered the Project\u2019s delivery, requiring the collation of extensive documentation evidencing the progress of the Project and several days of interviews with key stakeholders. Conclusions of each review were shared across delivery partners to inform successful delivery of the Project.<\/p>
The Department, Genomics England and NHS England recognised the importance in embedding robust testing, assessment and evaluation throughout the delivery of the Project to inform the introduction of whole genome sequencing in the National Health Service under the new Genomics Medicine Service.<\/p>
<\/p>"} , "answeringMember" : {"_about" : "http://data.parliament.uk/members/4008", "label" : {"_value" : "Biography information for Dame Caroline Dinenage"} } , "answeringMemberConstituency" : {"_value" : "Gosport"} , "answeringMemberPrinted" : {"_value" : "Caroline Dinenage"} , "dateOfAnswer" : {"_value" : "2019-07-05", "_datatype" : "dateTime"} , "isMinisterialCorrection" : {"_value" : "false", "_datatype" : "boolean"} , "questionFirstAnswered" : [{"_value" : "2019-07-05T11:40:47Z", "_datatype" : "dateTime"} ]} , "answeringDeptId" : {"_value" : "17"} , "answeringDeptShortName" : {"_value" : "Health and Social Care"} , "answeringDeptSortName" : {"_value" : "Health and Social Care"} , "date" : {"_value" : "2019-06-26", "_datatype" : "dateTime"} , "hansardHeading" : {"_value" : "100,000 Genomes Project"} , "houseId" : {"_value" : "1"} , "legislature" : [{"_about" : "http://data.parliament.uk/terms/25259", "prefLabel" : {"_value" : "House of Commons"} } ], "questionText" : "To ask the Secretary of State for Health and Social Care, what plans his Department has to evaluate the 100,000 Genomes Project.", "registeredInterest" : {"_value" : "false", "_datatype" : "boolean"} , "tablingMember" : {"_about" : "http://data.parliament.uk/members/4370", "label" : {"_value" : "Biography information for Jess Phillips"} } , "tablingMemberConstituency" : {"_value" : "Birmingham, Yardley"} , "tablingMemberPrinted" : [{"_value" : "Jess Phillips"} ], "uin" : "269788"} , {"_about" : "http://data.parliament.uk/resources/855777", "AnsweringBody" : [{"_value" : "Department of Health and Social Care"} ], "answer" : {"_about" : "http://data.parliament.uk/resources/855777/answer", "answerText" : {"_value" : "
The project is regularly reviewed by Infrastructure and Projects Authority which provides independent assurance to the most complex and strategically significant projects across Government.<\/p>
<\/p>
A number of pilot sites were in operation prior to the start of the 100,000 Genomes Project. Following the evaluation of these pilot projects, processes were put in place for how the 100,000 Genomes Project is delivered at scale across the country.<\/p>
<\/p>
Learning from the 100,000 Genomes Project has been key to the development of a new National Genomic Medicine Service and National Genomic Test Directory by the National Health Service in England both of which will become operational in autumn 2018.<\/p>
<\/p>
A study \u2018Understanding Experiences of Recruiting for and Participating in Genomics Research\u2019 is being undertaken at the Departmental\u2013funded Policy Innovation Research Unit. The study will include people's experience of taking part in the 100,000 Genomes Project and is due to report in 2018.<\/p>"} , "answeringMember" : {"_about" : "http://data.parliament.uk/members/4065", "label" : {"_value" : "Biography information for Dame Jackie Doyle-Price"} } , "answeringMemberConstituency" : {"_value" : "Thurrock"} , "answeringMemberPrinted" : {"_value" : "Jackie Doyle-Price"} , "dateOfAnswer" : {"_value" : "2018-03-08", "_datatype" : "dateTime"} , "isMinisterialCorrection" : {"_value" : "false", "_datatype" : "boolean"} , "questionFirstAnswered" : [{"_value" : "2018-03-08T11:58:34.043Z", "_datatype" : "dateTime"} ]} , "answeringDeptId" : {"_value" : "17"} , "answeringDeptShortName" : {"_value" : "Health and Social Care"} , "answeringDeptSortName" : {"_value" : "Health and Social Care"} , "date" : {"_value" : "2018-03-05", "_datatype" : "dateTime"} , "hansardHeading" : {"_value" : "100,000 Genomes Project"} , "houseId" : {"_value" : "1"} , "legislature" : [{"_about" : "http://data.parliament.uk/terms/25259", "prefLabel" : {"_value" : "House of Commons"} } ], "questionText" : "To ask the Secretary of State for Health and Social Care, whether the Government has plans to commission an external evaluation of the 100,000 genomes project.", "registeredInterest" : {"_value" : "false", "_datatype" : "boolean"} , "tablingMember" : {"_about" : "http://data.parliament.uk/members/4124", "label" : {"_value" : "Biography information for Chi Onwurah"} } , "tablingMemberConstituency" : {"_value" : "Newcastle upon Tyne Central"} , "tablingMemberPrinted" : [{"_value" : "Chi Onwurah"} ], "uin" : "131082"} , {"_about" : "http://data.parliament.uk/resources/456173", "AnsweringBody" : [{"_value" : "Department of Health"} ], "answer" : {"_about" : "http://data.parliament.uk/resources/456173/answer", "answerText" : {"_value" : "
The 100,000 Genomes Project could potentially diagnose participants with a ring chromosome through whole genome sequencing. The close working between NHS Genomic Medicine Centres and Genomics England means that ring chromosomes will continue to be detected primarily through routine diagnostic care. The 100,000 Genomes Project will give important information on the effective use of genomic technologies to bring benefit to National Health Service patients.<\/p>"} , "answeringMember" : {"_about" : "http://data.parliament.uk/members/4020", "label" : {"_value" : "Biography information for George Freeman"} } , "answeringMemberConstituency" : {"_value" : "Mid Norfolk"} , "answeringMemberPrinted" : {"_value" : "George Freeman"} , "dateOfAnswer" : {"_value" : "2016-03-08", "_datatype" : "dateTime"} , "isMinisterialCorrection" : {"_value" : "false", "_datatype" : "boolean"} , "questionFirstAnswered" : [{"_value" : "2016-03-08T11:36:26.213Z", "_datatype" : "dateTime"} ]} , "answeringDeptId" : {"_value" : "17"} , "answeringDeptShortName" : {"_value" : "Health"} , "answeringDeptSortName" : {"_value" : "Health"} , "date" : {"_value" : "2016-02-29", "_datatype" : "dateTime"} , "hansardHeading" : {"_value" : "100,000 Genomes Project"} , "houseId" : {"_value" : "1"} , "legislature" : [{"_about" : "http://data.parliament.uk/terms/25259", "prefLabel" : {"_value" : "House of Commons"} } ], "questionText" : "To ask the Secretary of State for Health, whether the 100,000 Genomes project will be able to diagnose patients with a ring chromosome.", "registeredInterest" : {"_value" : "false", "_datatype" : "boolean"} , "tablingMember" : {"_about" : "http://data.parliament.uk/members/4445", "label" : {"_value" : "Biography information for Ben Howlett"} } , "tablingMemberConstituency" : {"_value" : "Bath"} , "tablingMemberPrinted" : [{"_value" : "Ben Howlett"} ], "uin" : "28890"} , {"_about" : "http://data.parliament.uk/resources/422076", "AnsweringBody" : [{"_value" : "Department of Health"} ], "answer" : {"_about" : "http://data.parliament.uk/resources/422076/answer", "answerText" : {"_value" : "
Almost 10,000 people have been involved in the 100,000 Genomes Project so far,with more joining through the NHS Genomic Medicine Centres each day.The Project will sequence 100,000 whole genomes from around 70,000 people.Cancer patients have their genome and the genome of their cancer sequenced. Rare disease patients have their genome sequenced as do two of their blood relatives.<\/p>
As at 12 October 5,234 whole genomes had been sequenced and added to the data centre.Substantial progress has been made across all aims of the project including the establishment of 11 NHS Genomics Medicine Centres who are actively recruiting participants and the first rare disease patients being diagnosed.<\/p>
Regular updates on the 100,000 Genomes Project including the total number of genomes sequenced are published on Genomics England\u2019s website:<\/p>
www.genomicsengland.co.uk<\/a><\/p>"}
, "answeringMember" : {"_about" : "http://data.parliament.uk/members/127", "label" : {"_value" : "Biography information for Lord Prior of Brampton"}
}
, "answeringMemberPrinted" : {"_value" : "Lord Prior of Brampton"}
, "dateOfAnswer" : {"_value" : "2015-10-28", "_datatype" : "dateTime"}
, "groupedQuestionUIN" : [{"_value" : "HL2697"}
, {"_value" : "HL2698"}
], "isMinisterialCorrection" : {"_value" : "false", "_datatype" : "boolean"}
, "questionFirstAnswered" : [{"_value" : "2015-10-28T12:28:10.8Z", "_datatype" : "dateTime"}
]}
, "answeringDeptId" : {"_value" : "17"}
, "answeringDeptShortName" : {"_value" : "Health"}
, "answeringDeptSortName" : {"_value" : "Health"}
, "date" : {"_value" : "2015-10-19", "_datatype" : "dateTime"}
, "hansardHeading" : {"_value" : "100,000 Genomes Project"}
, "houseId" : {"_value" : "2"}
, "legislature" : [{"_about" : "http://data.parliament.uk/terms/25277", "prefLabel" : {"_value" : "House of Lords"}
}
], "questionText" : "To ask Her Majesty\u2019s Government what progress they have made in meeting their target of collecting and sequencing 100,000 human genomes by 2017.", "registeredInterest" : {"_value" : "false", "_datatype" : "boolean"}
, "tablingMember" : {"_about" : "http://data.parliament.uk/members/2024", "label" : {"_value" : "Biography information for Lord Hunt of Kings Heath"}
}
, "tablingMemberPrinted" : [{"_value" : "Lord Hunt of Kings Heath"}
], "uin" : "HL2696"}
, {"_about" : "http://data.parliament.uk/resources/422077", "AnsweringBody" : [{"_value" : "Department of Health"}
], "answer" : {"_about" : "http://data.parliament.uk/resources/422077/answer", "answerText" : {"_value" : " Almost 10,000 people have been involved in the 100,000 Genomes Project so far,with more joining through the NHS Genomic Medicine Centres each day.The Project will sequence 100,000 whole genomes from around 70,000 people.Cancer patients have their genome and the genome of their cancer sequenced. Rare disease patients have their genome sequenced as do two of their blood relatives.<\/p> As at 12 October 5,234 whole genomes had been sequenced and added to the data centre.Substantial progress has been made across all aims of the project including the establishment of 11 NHS Genomics Medicine Centres who are actively recruiting participants and the first rare disease patients being diagnosed.<\/p> Regular updates on the 100,000 Genomes Project including the total number of genomes sequenced are published on Genomics England\u2019s website:<\/p>