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1039028

	registered interest
	date	10/01/2019
	answering body	Department of Health and Social Care
	answering dept id	17
	answering dept short name	Health and Social Care
	answering dept sort name	Health and Social Care
	hansard heading	Asparaginase
	house id	1
	legislature	25259 pref label House of Commons
	question text	To ask the Secretary of State for Health and Social Care, whether Erwinase will be available for the treatment for children with acute lymphoblastic leukaemia between January 2019 and March 2019; and if he will make a statement.
	tabling member constituency	Crawley
	tabling member printed	Henry Smith
	uin	207238
	answer	answer is ministerial correction date of answer 18/01/2019 answer text <p>Erwinase is produced by Porton Biopharma Ltd (PBL) and is licensed and distributed by Jazz Pharmaceuticals under a global licencing agreement.</p><p> </p><p>Due to increased demand for Erwinase and because PBL are manufacturing at capacity, until increases in capacity are brought into beneficial use there will be occasional stock-outs.</p><p> </p><p>The product is currently in stock in the United Kingdom. The Department has been informed, it is likely there will be a short stock-out in early February 2019 and then a further batch is planned to be released to Jazz Pharmaceuticals, who are responsible for the packaging/distribution and allocation of worldwide product supply, anticipated to reach the UK market by mid-February 2019 which should last until the end of March 2019.</p><p> </p><p>The Department and Public Health England (PHE) are in close contact with, and have been kept informed by the PBL management of short periods of interrupted supply. PBL have and will be implementing a series of initiatives to increase capacity and better supply the market in both the short and long term. PBL are fully aware of the consequences that the unavailability of Erwinase has on patients and are absolutely committed to working with all involved to resolve any issues and be able to supply this critical medicine.</p><p> </p><p>The Department and PHE will continue to monitor the situation closely.</p> answering member constituency Winchester answering member printed Steve Brine question first answered 18/01/2019 12:18:00 answering member 4067 label Biography information for Steve Brine
	tabling member	3960 label Biography information for Henry Smith

1050101

	registered interest
	date	28/01/2019
	answering body	Department of Health and Social Care
	answering dept id	17
	answering dept short name	Health and Social Care
	answering dept sort name	Health and Social Care
	hansard heading	Asparaginase
	house id	1
	legislature	25259 pref label House of Commons
	question text	To ask the Secretary of State for Health and Social Care, pursuant to the Answer of 18 January 2019 to Question 207238 on Asparaginase, what steps Porton Biopharma will take to increase capacity of erwinase and better supply the (a) UK and (b) world market for the remainder of 2019.
	tabling member constituency	Crawley
	tabling member printed	Henry Smith
	uin	213322
	answer	answer is ministerial correction date of answer 05/02/2019 answer text <p>Porton Biopharma Ltd (PBL) are implementing a series of initiatives to increase capacity and supply in both the short and long term. These include the following:</p><p>- Extending operational activities to 24 hours a day, seven days a week to maximise fermentation of the product;</p><p>- Implementing an ongoing capital programme including construction of a new pharmaceutical fermentation facility. The facility was completed in April 2018 and is currently undergoing testing; it has an increased capacity fermentation suite which will enable PBL to manufacture at larger scale and is due to start producing product Q3 2019 for regulatory approval to market;</p><p>- A new filling and freeze-drying building was completed in February 2016. The installation of a new filling line which covers the entire process, including vial washing, filling, stoppering and freeze drying. The new line has been designed with systems which monitor all critical parameters throughout the process to accelerate batch release and will accommodate increased capacity. The beneficial use of this and the fermentation facility will coincide to maximise increased product output; and</p><p>- Sourcing replacement suppliers, including for new stoppers and new vials for the product, ensuring that maximum batch sizes can be achieved with minimal product rejects. This programme is complete.</p><p> </p><p>PBL has made significant investments into increasing product capacity and will continue to release future batches as soon as they become available to Jazz Pharmaceuticals (who are responsible for the packaging/distribution and allocation of worldwide product supply).</p> answering member constituency Winchester answering member printed Steve Brine question first answered 05/02/2019 15:09:48 answering member 4067 label Biography information for Steve Brine
	tabling member	3960 label Biography information for Henry Smith

1231662

	registered interest
	date	04/09/2020
	answering body	Department of Health and Social Care
	answering dept id	17
	answering dept short name	Health and Social Care
	answering dept sort name	Health and Social Care
	hansard heading	Asthma
	house id	1
	legislature	25259 pref label House of Commons
	question text	To ask the Secretary of State for Health and Social Care, pursuant to the Answer of 25 June 2020 to Question 58767, what plans he has to centrally collate data on the total number of severe asthma patients (a) in England and (b) within each of the NHS E+I regions.
	tabling member constituency	Crawley
	tabling member printed	Henry Smith
	uin	85020
	answer	answer is ministerial correction date of answer 22/09/2020 answer text <p>There are no plans for this.</p> answering member constituency Faversham and Mid Kent answering member printed Helen Whately question first answered 22/09/2020 14:46:46 answering member 4527 label Biography information for Helen Whately
	tabling member	3960 label Biography information for Henry Smith

1231661

	registered interest
	date	04/09/2020
	answering body	Department of Health and Social Care
	answering dept id	17
	answering dept short name	Health and Social Care
	answering dept sort name	Health and Social Care
	hansard heading	Asthma: Medical Treatments
	house id	1
	legislature	25259 pref label House of Commons
	question text	To ask the Secretary of State for Health and Social Care, pursuant to the Answer of 22 June 2020 to Question 58769, what assessment he has made of the decline to the number of patients accessing biologics therapies for severe asthma in January to March 2020, and what he has to reverse that decline.
	tabling member constituency	Crawley
	tabling member printed	Henry Smith
	uin	85019
	answer	answer is ministerial correction date of answer 19/10/2020 answer text <p>The National Institute for Health and Care Excellence COVID-19 rapid guideline on severe asthma provides guidance on starting or continuing on biological treatments, for people with severe asthma during the COVID-19 outbreak. The recommendations were written in collaboration with the NHS England Severe Asthma Collaborative. In writing the guidance, particular attention was paid to streamlining the process of moving patients onto biologic therapies to compensate for any possible barriers that may have occurred as a result of changes to the National Health Service, which were made as part of the necessary response to COVID-19.</p><p>Further work is being undertaken by the collaborative to share best practice on providing care to people with severe asthma to ensure on-going provision of high-quality care and to accelerate the initiation of biologics where required.</p> answering member constituency Faversham and Mid Kent answering member printed Helen Whately question first answered 19/10/2020 10:33:39 answering member 4527 label Biography information for Helen Whately
	tabling member	3960 label Biography information for Henry Smith

1172698

	registered interest
	date	22/01/2020
	answering body	Department of Health and Social Care
	answering dept id	17
	answering dept short name	Health and Social Care
	answering dept sort name	Health and Social Care
	hansard heading	Blood Cancer
	house id	1
	legislature	25259 pref label House of Commons
	question text	To ask the Secretary of State for Health and Social Care, what plans he has to reduce the number of people with blood cancer visiting their GP three or more times.
	tabling member constituency	Crawley
	tabling member printed	Henry Smith
	uin	6642
	answer	answer is ministerial correction date of answer 31/01/2020 answer text <p>In 2020, NHS England and NHS Improvement will continue to roll-out Rapid Diagnostic Centres across the country to upgrade and bring together the latest diagnostic equipment and expertise. They will initially focus on diagnosing cancers where patients often present with non-specific symptoms, such as blood cancer, and may go to their general practitioner many times before being sent for appropriate tests.</p><p> </p><p> </p><p> </p> answering member constituency Bury St Edmunds answering member printed Jo Churchill question first answered 31/01/2020 11:10:11 answering member 4380 label Biography information for Jo Churchill
	tabling member	3960 label Biography information for Henry Smith

1190700

	registered interest
	date	27/04/2020
	answering body	Department of Health and Social Care
	answering dept id	17
	answering dept short name	Health and Social Care
	answering dept sort name	Health and Social Care
	hansard heading	Blood Cancer: Coronavirus
	house id	1
	legislature	25259 pref label House of Commons
	question text	To ask the Secretary of State for Health and Social Care, how many people with blood cancer have received a letter asking them to shield at home for 12 weeks from (a) NHS England and (b) their local clinical care team; and how many of those people have (i) chronic lymphocytic leukaemia and (ii) Myeloproliferative neoplasms.
	tabling member constituency	Crawley
	tabling member printed	Henry Smith
	uin	40578
	answer	answer is ministerial correction date of answer 18/06/2020 answer text <p>As of May 2020, 164,427 patients had been identified in the category “people with cancers of the blood or bone marrow such as leukaemia, lymphoma or myeloma who are at any stage of treatment” by NHS Digital, and received a letter asking them to shield at home for 12 weeks. The information about how many patients in this category identified locally is not held centrally.</p> answering member constituency Bury St Edmunds answering member printed Jo Churchill question first answered 18/06/2020 17:05:07 answering member 4380 label Biography information for Jo Churchill
	tabling member	3960 label Biography information for Henry Smith

1193071

	registered interest
	date	05/05/2020
	answering body	Department of Health and Social Care
	answering dept id	17
	answering dept short name	Health and Social Care
	answering dept sort name	Health and Social Care
	hansard heading	Blood Cancer: Coronavirus
	house id	1
	legislature	25259 pref label House of Commons
	question text	To ask the Secretary of State for Health and Social Care, how many (a) men (b) women with blood cancer in each age group have (i) contracted covid-19 (ii) received intensive care support and (iii) died with covid-19.
	tabling member constituency	Crawley
	tabling member printed	Henry Smith
	uin	43625
	answer	answer is ministerial correction date of answer 29/05/2020 answer text <p>This data is not currently held.</p> answering member constituency Bury St Edmunds answering member printed Jo Churchill question first answered 29/05/2020 15:07:52 answering member 4380 label Biography information for Jo Churchill
	tabling member	3960 label Biography information for Henry Smith

1199796

	registered interest
	date	02/06/2020
	answering body	Department of Health and Social Care
	answering dept id	17
	answering dept short name	Health and Social Care
	answering dept sort name	Health and Social Care
	hansard heading	Blood Cancer: Coronavirus
	house id	1
	legislature	25259 pref label House of Commons
	question text	To ask the Secretary of State for Health and Social Care, how many people with blood cancer have been removed from the shielding list by (a) clinicians and (b) GPs in England.
	tabling member constituency	Crawley
	tabling member printed	Henry Smith
	uin	53399
	answer	answer is ministerial correction date of answer 12/06/2020 answer text <p>The shielded patient list is dynamic – general practitioners and specialists continue to make clinical judgements based the shielding criteria, that may result in those who had initially been advised to shield from COVID-19 no longer being advised to do so. Doctors have also been provided with guidance to support these decisions, which should be made following discussion with the patient and taking into account their individual clinical circumstances.</p><p>Information on the number of patients removed from the shielded patient list is not held centrally.</p><p> </p><p> </p> answering member constituency Bury St Edmunds answering member printed Jo Churchill grouped question UIN 53400 question first answered 12/06/2020 12:24:33 answering member 4380 label Biography information for Jo Churchill
	tabling member	3960 label Biography information for Henry Smith

1199797

	registered interest
	date	02/06/2020
	answering body	Department of Health and Social Care
	answering dept id	17
	answering dept short name	Health and Social Care
	answering dept sort name	Health and Social Care
	hansard heading	Blood Cancer: Coronavirus
	house id	1
	legislature	25259 pref label House of Commons
	question text	To ask the Secretary of State for Health and Social Care, what evidence his Department based it's decision on for the removal of blood cancer patients from the covid-19 shielding list.
	tabling member constituency	Crawley
	tabling member printed	Henry Smith
	uin	53400
	answer	answer is ministerial correction date of answer 12/06/2020 answer text <p>The shielded patient list is dynamic – general practitioners and specialists continue to make clinical judgements based the shielding criteria, that may result in those who had initially been advised to shield from COVID-19 no longer being advised to do so. Doctors have also been provided with guidance to support these decisions, which should be made following discussion with the patient and taking into account their individual clinical circumstances.</p><p>Information on the number of patients removed from the shielded patient list is not held centrally.</p><p> </p><p> </p> answering member constituency Bury St Edmunds answering member printed Jo Churchill grouped question UIN 53399 question first answered 12/06/2020 12:24:33 answering member 4380 label Biography information for Jo Churchill
	tabling member	3960 label Biography information for Henry Smith

1182699

	registered interest
	date	04/03/2020
	answering body	Department of Health and Social Care
	answering dept id	17
	answering dept short name	Health and Social Care
	answering dept sort name	Health and Social Care
	hansard heading	Blood Cancer: Diagnosis
	house id	1
	legislature	25259 pref label House of Commons
	question text	To ask the Secretary of State for Health and Social Care, what plans his Department has to reduce the number of people who first receive a diagnosis of blood cancer in hospital A&E units.
	tabling member constituency	Crawley
	tabling member printed	Henry Smith
	uin	25075
	answer	answer is ministerial correction date of answer 13/03/2020 answer text <p>The NHS Long Term Plan sets out an ambition that, by 2028, the proportion of cancers diagnosed at stages 1 and 2 will rise from around half to three-quarters of cancer patients.</p><p>Other key actions to increase an early diagnosis of blood cancer are:</p><p>- campaigns to raise greater awareness of the symptoms of cancer;</p><p>- lowering the threshold for referral by general practitioners (GPs);</p><p>- accelerate access to diagnosis and treatment and maximise the number of cancers that specialist’s can identify through screening; and</p><p>- roll-out of new Rapid Diagnostic Centres across the country to</p><p>- upgrade and bring together the latest diagnostic equipment and expertise.</p><p> </p><p>The Long Term Plan also commits to invest £4.5 billion of new funding to establish Primary Care Networks based on neighbouring GP practices. The GP Contract, published on 6 February 2020, includes a new service specification for supporting early cancer diagnosis, including blood cancer.</p><p> </p> answering member constituency Bury St Edmunds answering member printed Jo Churchill question first answered 13/03/2020 12:18:16 answering member 4380 label Biography information for Jo Churchill
	tabling member	3960 label Biography information for Henry Smith