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1646649

	registered interest
	date	22/06/2023
	answering body	Department of Health and Social Care
	answering dept id	17
	answering dept short name	Health and Social Care
	answering dept sort name	Health and Social Care
	hansard heading	Radiotherapy: Health Professions:
	house id	1
	legislature	25259 pref label House of Commons
	question text	To ask the Secretary of State for Health and Social Care, if he will include provisions in the NHS workforce plan to increase the nuclear medicines workforce; and what steps he is taking to ensure the adequacy of supply of that workforce to meet future demand for (a) molecular radiotherapy and (b) other treatments.
	tabling member constituency	Mid Derbyshire
	tabling member printed	Mrs Pauline Latham
	uin	190787
	answer	answer is ministerial correction date of answer 27/06/2023 answer text <p>The Government has committed to publishing the Long-Term Workforce Plan shortly. This will include projections for the number of doctors, nurses and other professionals that will be needed, taking full account of improvements in retention and productivity. This plan will help ensure that we have the right numbers of staff, with the right skills, to transform and deliver high quality services fit for the future.</p><p>NHS England are currently leading work to revise the Brachytherapy and Molecular Radiotherapy Service Specification and to understand current service readiness to expand access to new molecular radiotherapy treatments, should they be approved by National Institute for Health and Care Excellence.</p> answering member constituency Colchester answering member printed Will Quince question first answered 27/06/2023 15:27:28 answering member 4423 label Biography information for Will Quince
	tabling member	4025 label Biography information for Mrs Pauline Latham

768962

	registered interest
	date	11/10/2017
	answering body	Department of Health
	answering dept id	17
	answering dept short name	Health
	answering dept sort name	Health
	hansard heading	Diabetes and Hypertension: Pharmacy
	house id	1
	legislature	25259 pref label House of Commons
	question text	To ask the Secretary of State for Health, what plans his Department has to evolve Medicines Use Reviews to enable community pharmacists to better support people with long-term conditions such as diabetes and high blood pressure.
	tabling member constituency	Mid Derbyshire
	tabling member printed	Pauline Latham
	uin	107290
	answer	answer is ministerial correction date of answer 19/10/2017 answer text <p>The Department is committed to supporting people with long term conditions manage their illness and take their medication correctly. In line with this ambition, eligibility for Medicine Use Reviews was amended from April 2015, to better target these services at patients who would derive the most benefit from it. This change required 70% of Medicine Use Reviews to be held with people within key target groups which included people with conditions such as diabetes or high blood pressure.</p><p> </p><p>The Department continues to develop and monitor the evidence base and effectiveness of all Advanced Services provided by community pharmacists to improve patient outcomes and make the best use of National Health Service resources. It will continue to do so and develop plans accordingly.</p> answering member constituency Winchester answering member printed Steve Brine question first answered 19/10/2017 16:24:21 answering member 4067 label Biography information for Steve Brine
	tabling member	4025 label Biography information for Mrs Pauline Latham

1123233

	registered interest
	date	25/04/2019
	answering body	Department of Health and Social Care
	answering dept id	17
	answering dept short name	Health and Social Care
	answering dept sort name	Health and Social Care
	hansard heading	Aortic Dissection: Diagnosis
	house id	1
	legislature	25259 pref label House of Commons
	question text	To ask the Secretary of State for Health and Social Care, what steps are being taken to help improve diagnosis of Aortic Dissection.
	tabling member constituency	Mid Derbyshire
	tabling member printed	Mrs Pauline Latham
	uin	247675
	answer	answer is ministerial correction date of answer 03/05/2019 answer text <p>NHS England Specialised Commissioning has a published service specification for cardiac surgery, to support national standards, which include this highly serious condition.</p><p>It is recognised that survival rates for emergency interventions are better when care is delivered by a surgeon supported by interventional specialists undertaking higher volumes of these procedures. This point was also highlighted in the Cardiac Surgery Getting It Right First Time (GIRFT) 2018 document, and the NHS England Specialised Cardiac Improvement cardiac surgery work stream is taking forward the GIRFT recommendations, which will also look at how pathways of care for this and other specialised cardiac conditions can be improved by better network working across providers.</p> answering member constituency South Ribble answering member printed Seema Kennedy question first answered 03/05/2019 13:03:21 answering member 4455 label Biography information for Seema Kennedy
	tabling member	4025 label Biography information for Mrs Pauline Latham

1123235

	registered interest
	date	25/04/2019
	answering body	Department of Health and Social Care
	answering dept id	17
	answering dept short name	Health and Social Care
	answering dept sort name	Health and Social Care
	hansard heading	Aortic Dissection: Tomography
	house id	1
	legislature	25259 pref label House of Commons
	question text	To ask the Secretary of State for Health and Social Care, what assessment he has made of the adequacy of the frequency of CT scanning in relation to aortic dissection; and what plans he has to increase the speed of access to that service.
	tabling member constituency	Mid Derbyshire
	tabling member printed	Mrs Pauline Latham
	uin	247676
	answer	answer is ministerial correction date of answer 03/05/2019 answer text <p>It is recognised the demand for cardiothoracic CT scanning procedures has increased considerably in recent years, for a number of indications.</p><p>The NHS Long Term Plan has identified the need to undertake an assessment of the capacity and demand for CT, including workforce implications.</p> answering member constituency South Ribble answering member printed Seema Kennedy question first answered 03/05/2019 11:07:28 answering member 4455 label Biography information for Seema Kennedy
	tabling member	4025 label Biography information for Mrs Pauline Latham

1123236

	registered interest
	date	25/04/2019
	answering body	Department of Health and Social Care
	answering dept id	17
	answering dept short name	Health and Social Care
	answering dept sort name	Health and Social Care
	hansard heading	Heart Diseases: Surgery
	house id	1
	legislature	25259 pref label House of Commons
	question text	To ask the Secretary of State for Health and Social Care, what specialist aortic surgery facilities there are in the UK; and if he will make an assessment of the potential merits of introducing more specialist aortic surgery centres.
	tabling member constituency	Mid Derbyshire
	tabling member printed	Mrs Pauline Latham
	uin	247677
	answer	answer is ministerial correction date of answer 03/05/2019 answer text <p>There are currently 28 specialised cardiac surgery centres in England.</p><p>NHS England and NHS Improvement has advised that the Specialised Cardiac Improvement Programme includes a workstream on cardiac surgery, but this and previous work has not identified the need for additional surgical centres. The aim is to further develop networked centres to increase access to surgeons who have developed and can maintain particular expertise in aortic dissection surgery.</p> answering member constituency South Ribble answering member printed Seema Kennedy question first answered 03/05/2019 11:03:26 answering member 4455 label Biography information for Seema Kennedy
	tabling member	4025 label Biography information for Mrs Pauline Latham

1123241

	registered interest
	date	25/04/2019
	answering body	Department of Health and Social Care
	answering dept id	17
	answering dept short name	Health and Social Care
	answering dept sort name	Health and Social Care
	hansard heading	Hypertension: Clinics
	house id	1
	legislature	25259 pref label House of Commons
	question text	To ask the Secretary of State for Health and Social Care, if he will make an assessment of the potential merits of establishing additional specialist blood pressure clinics.
	tabling member constituency	Mid Derbyshire
	tabling member printed	Mrs Pauline Latham
	uin	247679
	answer	answer is ministerial correction date of answer 03/05/2019 answer text <p>The number of individuals with resistant hypertension, requiring highly specialist input, is small and there are specialist clinics across the country.</p><p>NHS England and NHS Improvement has advised that the vast majority of people with hypertension will be satisfactorily managed in primary care, often with support from hospital specialists across cardiology, renal medicine, and clinical pharmacology.</p> answering member constituency South Ribble answering member printed Seema Kennedy question first answered 03/05/2019 13:04:25 answering member 4455 label Biography information for Seema Kennedy
	tabling member	4025 label Biography information for Mrs Pauline Latham

1313878

	registered interest
	date	12/05/2021
	answering body	Department of Health and Social Care
	answering dept id	17
	answering dept short name	Health and Social Care
	answering dept sort name	Health and Social Care
	hansard heading	Antibiotics: Side Effects
	house id	1
	legislature	25259 pref label House of Commons
	question text	To ask the Secretary of State for Health and Social Care, what steps he is taking to increase awareness of fluoroquinolone toxicity among healthcare professionals.
	tabling member constituency	Mid Derbyshire
	tabling member printed	Mrs Pauline Latham
	uin	684
	answer	answer is ministerial correction date of answer 19/05/2021 answer text <p>The Medicines and Healthcare products Regulatory Agency (MHRA) has issued reminders for healthcare professionals that fluoroquinolones should not be used in conditions that are not serious or improve on their own and that they should only be used for acute episodes of chronic bronchitis and uncomplicated cystitis if other antibiotics cannot be used.</p><p>This also includes stronger warnings about the potential side effects of fluoroquinolones in the product information for healthcare professionals and for patients and mandating pharmaceutical companies to issue letters to healthcare professionals on the new restrictions and stronger warnings about these serious risks, including signs and symptoms which can appear.</p><p> </p><p>The MHRA is working with the National Institute for Health and Care Excellence and the British National Formulary to promote appropriate use of fluoroquinolones and ensure that the restrictions are aligned with United Kingdom national guidance on the antibiotic treatment of infections.</p> answering member constituency Mid Bedfordshire answering member printed Ms Nadine Dorries question first answered 19/05/2021 11:01:03 answering member 1481 label Biography information for Ms Nadine Dorries previous answer version 380 answering member constituency Mid Bedfordshire answering member printed Ms Nadine Dorries answering member 1481 label Biography information for Ms Nadine Dorries
	tabling member	4025 label Biography information for Mrs Pauline Latham

1327742

	registered interest
	date	25/05/2021
	answering body	Department of Health and Social Care
	answering dept id	17
	answering dept short name	Health and Social Care
	answering dept sort name	Health and Social Care
	hansard heading	Yellow Card Scheme
	house id	1
	legislature	25259 pref label House of Commons
	question text	To ask the Secretary of State for Health and Social Care, what assessment he has made of the extent of under-reporting of adverse drug reactions to the Yellow Card scheme.
	tabling member constituency	Mid Derbyshire
	tabling member printed	Mrs Pauline Latham
	uin	7153
	answer	answer is ministerial correction date of answer 07/06/2021 answer text <p>The reporting rate for spontaneous adverse drug reactions (ADR) is variable and can depend on a multitude of factors. Although some historical studies have estimated only 10% of ADRs are reported, the actual rate is unknown and variable because it is influenced by public awareness and seriousness of the event.</p> answering member constituency Mid Bedfordshire answering member printed Ms Nadine Dorries question first answered 07/06/2021 08:40:15 answering member 1481 label Biography information for Ms Nadine Dorries
	tabling member	4025 label Biography information for Mrs Pauline Latham

1327743

	registered interest
	date	25/05/2021
	answering body	Department of Health and Social Care
	answering dept id	17
	answering dept short name	Health and Social Care
	answering dept sort name	Health and Social Care
	hansard heading	Antibiotics: Side Effects
	house id	1
	legislature	25259 pref label House of Commons
	question text	To ask the Secretary of State for Health and Social Care, how many and what proportion of patients who are prescribed fluoroquinolone antibiotics suffer adverse reactions in the form of (a) tendon injury, (b) mitochondrial dysfunction and (c) oxidative stress.
	tabling member constituency	Mid Derbyshire
	tabling member printed	Mrs Pauline Latham
	uin	7154
	answer	answer is ministerial correction date of answer 09/06/2021 answer text <p>The Yellow Card Scheme is the system used in the United Kingdom for reporting adverse drug reactions (ADRs). This acts as an early warning system for the identification of previously unrecognised adverse reactions and also provides valuable information on recognised ADRs, allowing the Commission on Human Medicines and Medicines and Healthcare products Regulatory Agency (MHRA) to identify and refine the understanding of risk factors that may affect the clinical management of patients.</p><p> </p><p>The following table shows spontaneous suspected ADR reports for fluoroquinolones in association with tendon injury, mitochondrial dysfunction and oxidative stress to 25 May 2021 in the UK.</p><p> </p><table><tbody><tr><td><p>Reaction</p></td><td><p>Number of reports</p></td></tr><tr><td><p>Tendon disorders*</p></td><td><p>1,381</p></td></tr><tr><td><p>mitochondrial cytopathy, mitochondrial toxicity, mitochondrial myopathy acquired</p></td><td><p>1</p></td></tr><tr><td><p>Oxidative stress</p></td><td><p>2**</p></td></tr></tbody></table><p> </p><p>Source: MHRA Sentinel database for Adverse Drug Reactions.</p><p> </p><p>Notes:</p><p> </p><p>*Tendon disorders includes 21 different relevant reaction terms.</p><p>**These reports are duplicates and have been subsequently merged on the database.</p><p> </p><p>The frequency of tendonitis range from 1 in 100 to less than 1 in 10,000, depending on the specific fluoroquinolone medicine. For the products that provide an estimate of the frequency of tendon rupture, this is listed as less than 1 in 10,000. Mitochondrial dysfunction and oxidative stress are among the possible mechanisms that might lead to tendon injury or other ADRs caused by fluoroquinolones, but this association is not fully understood and mitochondrial dysfunction and oxidative stress are not listed as ADRs in the product information for fluoroquinolones.</p><p> </p><p>The MHRA continues to review information about the safety of all medicines, including fluoroquinolones, and will take appropriate regulatory action as appropriate on the basis of new safety information. Serious side effects of fluoroquinolone antibiotics can be varied, potentially affecting several different parts of the body. An assessment of the potential merits of fluoroquinolone toxicity as a clinical diagnosis in response to tendon injury, mitochondrial dysfunction or oxidative stress has not been made.</p> answering member constituency Mid Bedfordshire answering member printed Ms Nadine Dorries grouped question UIN 7155 question first answered 09/06/2021 09:32:28 answering member 1481 label Biography information for Ms Nadine Dorries previous answer version 4612 answering member constituency Mid Bedfordshire answering member printed Ms Nadine Dorries answering member 1481 label Biography information for Ms Nadine Dorries
	tabling member	4025 label Biography information for Mrs Pauline Latham

1327744

	registered interest
	date	25/05/2021
	answering body	Department of Health and Social Care
	answering dept id	17
	answering dept short name	Health and Social Care
	answering dept sort name	Health and Social Care
	hansard heading	Antibiotics: Side Effects
	house id	1
	legislature	25259 pref label House of Commons
	question text	To ask the Secretary of State for Health and Social Care, what recent assessment he has made of the potential merits of establishing fluoroquinolone toxicity as a diagnosis in response to (a) tendon injury, (b) mitochondrial dysfunction and (c) oxidative stress attributed by some patients to the use of that drug.
	tabling member constituency	Mid Derbyshire
	tabling member printed	Mrs Pauline Latham
	uin	7155
	answer	answer is ministerial correction date of answer 09/06/2021 answer text <p>The Yellow Card Scheme is the system used in the United Kingdom for reporting adverse drug reactions (ADRs). This acts as an early warning system for the identification of previously unrecognised adverse reactions and also provides valuable information on recognised ADRs, allowing the Commission on Human Medicines and Medicines and Healthcare products Regulatory Agency (MHRA) to identify and refine the understanding of risk factors that may affect the clinical management of patients.</p><p> </p><p>The following table shows spontaneous suspected ADR reports for fluoroquinolones in association with tendon injury, mitochondrial dysfunction and oxidative stress to 25 May 2021 in the UK.</p><p> </p><table><tbody><tr><td><p>Reaction</p></td><td><p>Number of reports</p></td></tr><tr><td><p>Tendon disorders*</p></td><td><p>1,381</p></td></tr><tr><td><p>mitochondrial cytopathy, mitochondrial toxicity, mitochondrial myopathy acquired</p></td><td><p>1</p></td></tr><tr><td><p>Oxidative stress</p></td><td><p>2**</p></td></tr></tbody></table><p> </p><p>Source: MHRA Sentinel database for Adverse Drug Reactions.</p><p> </p><p>Notes:</p><p> </p><p>*Tendon disorders includes 21 different relevant reaction terms.</p><p>**These reports are duplicates and have been subsequently merged on the database.</p><p> </p><p>The frequency of tendonitis range from 1 in 100 to less than 1 in 10,000, depending on the specific fluoroquinolone medicine. For the products that provide an estimate of the frequency of tendon rupture, this is listed as less than 1 in 10,000. Mitochondrial dysfunction and oxidative stress are among the possible mechanisms that might lead to tendon injury or other ADRs caused by fluoroquinolones, but this association is not fully understood and mitochondrial dysfunction and oxidative stress are not listed as ADRs in the product information for fluoroquinolones.</p><p> </p><p>The MHRA continues to review information about the safety of all medicines, including fluoroquinolones, and will take appropriate regulatory action as appropriate on the basis of new safety information. Serious side effects of fluoroquinolone antibiotics can be varied, potentially affecting several different parts of the body. An assessment of the potential merits of fluoroquinolone toxicity as a clinical diagnosis in response to tendon injury, mitochondrial dysfunction or oxidative stress has not been made.</p> answering member constituency Mid Bedfordshire answering member printed Ms Nadine Dorries grouped question UIN 7154 question first answered 09/06/2021 09:32:28 answering member 1481 label Biography information for Ms Nadine Dorries previous answer version 4615 answering member constituency Faversham and Mid Kent answering member printed Helen Whately answering member 4527
	tabling member	4025 label Biography information for Mrs Pauline Latham