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<p>The Global Burden of Disease (GBD) study provides a comprehensive picture of mortality
and disability across countries, time, age, and sex. It quantifies health loss from
hundreds of diseases, injuries, and risk factors, so that health systems can be improved
and disparities eliminated.</p><p>According to the data for England published by the
GBD study in 2019, the top 5 causes of years lived with disability for England were
low back pain, diabetes, depressive disorders, headache disorders and falls.</p><p>Data
for 2022 for England indicates that the five leading causes of death aged under 75
were cancers, cardiovascular diseases, respiratory diseases, deaths from external
causes, and digestive system diseases.</p><p>On the 24 January 2023, we announced
our plan to publish the Major Conditions Strategy. This strategy will explore how
we can tackle the key drivers of ill-health in England, reduce pressure on the NHS
and reduce ill-health related labour market inactivity.</p><p>To deliver on these
objectives, the strategy will focus on tackling the six major conditions groups –
cancers, mental ill-health, cardiovascular disease (including stroke and diabetes),
dementia, chronic respiratory diseases, and musculoskeletal disorders – that account
for around 60% of ill-health and early death in England.</p><p>Focusing on these groups
of conditions that contribute most to mortality and morbidity will allow us to focus
our efforts on the key actions needed to achieve our Levelling-Up mission to gain
five extra years of Healthy Life Expectancy by 2035.</p>
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