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105962

registered interest
date	03/11/2014
answering body	Department of Health
answering dept id	17
answering dept short name	Health
answering dept sort name	Health
hansard heading	IVF
house id	1
legislature	25259 pref label House of Commons
question text	To ask the Secretary of State for Health, what steps he is taking to reduce variation in the price of IVF cycles between clinical commissioning groups.
tabling member constituency	York Outer
tabling member printed	Julian Sturdy
uin	212894
answer	answer is ministerial correction date of answer 10/11/2014 answer text <p>For National Health Service funded in-vitro fertilisation treatment, it is for clinical commissioning groups to decide with which fertility clinics to contract and agree the price payable with the service provider.</p><p> </p> answering member constituency Battersea answering member printed Jane Ellison question first answered 10/11/2014 17:39:40 answering member 3918 label Biography information for Jane Ellison
tabling member	4079 label Biography information for Julian Sturdy

100550

registered interest
date	22/10/2014
answering body	Department of Health
answering dept id	17
answering dept short name	Health
answering dept sort name	Health
hansard heading	IVF
house id	2
legislature	25277 pref label House of Lords
question text	To ask Her Majesty’s Government, further to the Written Answers by Lord Darzi of Denham on 22 July 2008 (HL4926 and HL4927) and by Earl Howe on 9 July 2012 (HL1211), of how many cycles the Human Fertilisation and Embryology Authority are aware in which fresh embryo transfers took place after 15 or more eggs were collected over each of the past ten years.
tabling member printed	Lord Alton of Liverpool
uin	HL2287
answer	answer is ministerial correction date of answer 29/10/2014 answer text <p>The number of treatment cycles in which fresh embryo transfers took place after 15 or more eggs were collected, in each of the last 10 years, is shown in the following table:</p><p> </p><p> </p><p> </p><table><tbody><tr><td><p>Years</p></td><td><p>Cycles in which fresh embryo transfers took place after 15 or more eggs were collected</p></td></tr><tr><td><p>2004</p></td><td><p>5602</p></td></tr><tr><td><p>2005</p></td><td><p>5737</p></td></tr><tr><td><p>2006</p></td><td><p>5843</p></td></tr><tr><td><p>2007</p></td><td><p>6345</p></td></tr><tr><td><p>2008</p></td><td><p>6589</p></td></tr><tr><td><p>2009</p></td><td><p>7344</p></td></tr><tr><td><p>2010</p></td><td><p>7801</p></td></tr><tr><td><p>2011</p></td><td><p>8195</p></td></tr><tr><td><p>2012</p></td><td><p>8200</p></td></tr><tr><td><p>2013(1)</p></td><td><p>8128</p></td></tr></tbody></table><p> </p><p>Source: The Human Fertilisation and Embryology Authority</p><p> </p><p> </p><p> </p><p>(1) 2013 is the most recent year for which information is available.</p><p> </p> answering member printed Earl Howe question first answered 29/10/2014 12:25:39 answering member 2000 label Biography information for Earl Howe
tabling member	738 label Biography information for Lord Alton of Liverpool

99884

registered interest
date	20/10/2014
answering body	Department of Health
answering dept id	17
answering dept short name	Health
answering dept sort name	Health
hansard heading	IVF
house id	1
legislature	25259 pref label House of Commons
question text	To ask the Secretary of State for Health, where the unpublished, confidential evidence referred to in the updated Human Fertilisation and Embryology Authority report, Third scientific review of the safety and efficacy of methods to avoid mitochondrial disease through assisted conception will be published.
tabling member constituency	Congleton
tabling member printed	Fiona Bruce
uin	211181
answer	answer is ministerial correction date of answer 27/10/2014 answer text <p>The Human Fertilisation and Embryology Authority have advised that, by examining both published and unpublished research, the Expert Panel is able to take into account the very latest research on a confidential basis.</p><p> </p><p> </p><p> </p><p>Where the evidence is provided on a confidential basis, in time, that work will be published in peer reviewed journals. For example, some pieces of confidential evidence reviewed as part of the third scientific review have now been published in this way. These are:</p><p> </p><p> </p><p> </p><p>- Mitalipov, S. et al (2014). Limitations of Preimplantation Genetic Diagnosis for Mitochondrial DNA Diseases. Cell Reports 7(4);935-937</p><p> </p><p> </p><p> </p><p>- Chinnery PF. et al (2014) The challenges of mitochondrial replacement. PLoS Genet. 2014 24;10(4):e1004315</p><p> </p> answering member constituency Battersea answering member printed Jane Ellison question first answered 27/10/2014 17:02:21 answering member 3918 label Biography information for Jane Ellison
tabling member	3958 label Biography information for Fiona Bruce

93276

registered interest
date	14/10/2014
answering body	Department of Health
answering dept id	17
answering dept short name	Health
answering dept sort name	Health
hansard heading	IVF
house id	1
legislature	25259 pref label House of Commons
question text	To ask the Secretary of State for Health, when he plans to lay before the House regulations permitting mitochondrial replacement techniques.
tabling member constituency	Congleton
tabling member printed	Fiona Bruce
uin	210471
answer	answer is ministerial correction date of answer 21/10/2014 answer text <p>Following the publication on 22 July of the Government’s response to the consultation about the draft regulations to allow mitochondrial donation, the Government has been giving further consideration to the recommendations of the Expert Panel convened by the Human Fertilisation and Embryology Authority (HFEA), refining the draft regulations to take account of changes identified during the consultation, and discussing with the HFEA an appropriate approval process.</p><p> </p><p> </p><p> </p><p>Ministers will update Parliament on the Government’s intentions shortly.</p><p> </p> answering member constituency Battersea answering member printed Jane Ellison question first answered 21/10/2014 15:30:11 answering member 3918 label Biography information for Jane Ellison
tabling member	3958 label Biography information for Fiona Bruce

92961

registered interest
date	13/10/2014
answering body	Department of Health
answering dept id	17
answering dept short name	Health
answering dept sort name	Health
hansard heading	IVF
house id	1
legislature	25259 pref label House of Commons
question text	To ask the Secretary of State for Health, how many women aged over (a) 40 and (b) 50 received IVF in each of the last five years.
tabling member constituency	Strangford
tabling member printed	Jim Shannon
uin	210242
answer	answer is ministerial correction date of answer 20/10/2014 answer text <p>The number of women aged over 40 and 50 who received invitro fertilisation (IVF), for each of the last five years for which treatment data has been verified, is shown in the following table:</p><p> </p><p> </p><p> </p><table><tbody><tr><td><p>Years</p></td><td><p>Patients aged 40-49 undergoing IVF treatment</p></td><td><p>Patients aged 50 and over undergoing IVF treatment</p></td></tr><tr><td><p>2008</p></td><td><p>7,514</p></td><td><p>63</p></td></tr><tr><td><p>2009</p></td><td><p>7,938</p></td><td><p>56</p></td></tr><tr><td><p>2010</p></td><td><p>8,543</p></td><td><p>60</p></td></tr><tr><td><p>2011</p></td><td><p>8,708</p></td><td><p>68</p></td></tr><tr><td><p>2012</p></td><td><p>8,808</p></td><td><p>73</p></td></tr></tbody></table><p> </p><p><strong> </strong></p><p> </p><p><em>Notes:</em></p><p> </p><p>The years 2008-2012 have been supplied as 2012 is the last complete year that has been verified for treatment data.</p><p> </p><p><em> </em></p><p> </p><p><em>Source: </em>The Human Fertilisation and Embryology Authority</p><p> </p> answering member constituency Central Suffolk and North Ipswich answering member printed Dr Daniel Poulter question first answered 20/10/2014 16:51:26 answering member 3932 label Biography information for Dr Dan Poulter
tabling member	4131 label Biography information for Jim Shannon

92400

registered interest
date	06/10/2014
answering body	Department of Health
answering dept id	17
answering dept short name	Health
answering dept sort name	Health
hansard heading	IVF
house id	2
legislature	25277 pref label House of Lords
question text	To ask Her Majesty’s Government what assessment they have made of the risks of clinical trials of mitochondrial replacement therapy; and what safeguards will be put in place in such trials.
tabling member printed	Lord Alton of Liverpool
uin	HL1962
answer	answer is ministerial correction date of answer 20/10/2014 answer text <p>The safety and efficacy of two mitochondrial donation techniques proposed for clinical use, Maternal Spindle Transfer and Pronuclear Transfer, have been the subject of three scientific reviews carried out by an Expert Panel convened by the Human Fertilisation and Embryology Authority (HFEA). The Panel reported in April 2011, March 2013 and June 2014.</p><p> </p><p> </p><p> </p><p>Any regulations that would allow mitochondrial donation would also bring into place important safeguards through the HFEA’s licencing procedures. For a licence to be issued to a provider of mitochondrial donation they would first have to demonstrate that they could carry out the procedure safely and effectively.</p><p> </p> answering member printed Earl Howe question first answered 20/10/2014 17:02:15 answering member 2000 label Biography information for Earl Howe
tabling member	738 label Biography information for Lord Alton of Liverpool

92401

registered interest
date	06/10/2014
answering body	Department of Health
answering dept id	17
answering dept short name	Health
answering dept sort name	Health
hansard heading	IVF
house id	2
legislature	25277 pref label House of Lords
question text	To ask Her Majesty’s Government what assessment they have made of the role played by mitochondria in the development of an organism; and what they consider to be the implications of that assessment for mitochondrial replacement techniques.
tabling member printed	Lord Alton of Liverpool
uin	HL1963
answer	answer is ministerial correction date of answer 16/10/2014 answer text <p>As the noble Lord is aware, the Government commissioned the Human Fertilisation and Embryology Authority (HFEA) to convene an Expert Panel to review the science related to mitochondrial donation and the proposed donation techniques. The Panel produced reports on this in April 2011, March 2013 and June 2014. A description of the role of mitochondria can be found at paragraph 2.1 of the Expert Panel’s April 2011 scientific report. This can be found on the HFEA’s website at:</p><p> </p><p> </p><p> </p><p>www.hfea.gov.uk/6372.html</p><p> </p><p> </p><p> </p><p>The latest assessment of mitochondrial replacement techniques, carried out earlier this year by the Expert Panel, can be found at:</p><p> </p><p> </p><p> </p><p>www.hfea.gov.uk/8807.html</p><p> </p> answering member printed Earl Howe question first answered 16/10/2014 15:29:13 answering member 2000 label Biography information for Earl Howe
tabling member	738 label Biography information for Lord Alton of Liverpool

90845

registered interest
date	05/09/2014
answering body	Department of Health
answering dept id	17
answering dept short name	Health
answering dept sort name	Health
hansard heading	IVF
house id	1
legislature	25259 pref label House of Commons
question text	To ask the Secretary of State for Health, what assessment he has made of the potential effect of the authorisation of mitochondrial transfer techniques on the incidence of ovarian hyper stimulation syndrome; and if he will make a statement.
tabling member constituency	North Tyneside
tabling member printed	Mrs Mary Glindon
uin	208396
answer	answer is ministerial correction date of answer 11/09/2014 answer text <p> </p><p>The Human Fertilisation and Embryology Authority has advised that if mitochondria donation was permitted in treatment it is not anticipated that this will impact on the incidence of ovarian hyper stimulation syndrome.</p><p> </p> answering member constituency Battersea answering member printed Jane Ellison question first answered 11/09/2014 10:21:10 answering member 3918 label Biography information for Jane Ellison
tabling member	4126 label Biography information for Mary Glindon

90846

registered interest
date	05/09/2014
answering body	Department of Health
answering dept id	17
answering dept short name	Health
answering dept sort name	Health
hansard heading	IVF
house id	1
legislature	25259 pref label House of Commons
question text	To ask the Secretary of State for Health, what estimate he has made of the increase in the number of donor eggs that is needed to make mitochondrial transfer techniques practicable.
tabling member constituency	North Tyneside
tabling member printed	Mrs Mary Glindon
uin	208397
answer	answer is ministerial correction date of answer 11/09/2014 answer text <p> </p><p>The Human Fertilisation and Embryology Authority has advised that it has made no estimate of the number of donor eggs needed for mitochondrial replacement treatment.</p><p> </p> answering member constituency Battersea answering member printed Jane Ellison question first answered 11/09/2014 10:12:30 answering member 3918 label Biography information for Jane Ellison
tabling member	4126 label Biography information for Mary Glindon

90852

registered interest
date	05/09/2014
answering body	Department of Health
answering dept id	17
answering dept short name	Health
answering dept sort name	Health
hansard heading	IVF
house id	1
legislature	25259 pref label House of Commons
question text	To ask the Secretary of State for Health, if he will revise his definition of genetic modification to include manipulations of mitochondrial DNA.
tabling member constituency	Harrow East
tabling member printed	Bob Blackman
uin	208378
answer	answer is ministerial correction date of answer 12/09/2014 answer text <p> </p><p>The Department decided that, because there is no existing universally agreed definition of genetic modification in humans, it would adopt a working definition. The definition that has been adopted is that genetic modification involves the germ-line modification of nuclear DNA (in the chromosomes) that can be passed on to future generations.</p><p> </p><p> </p><p> </p><p>We have no current plans to revise the working definition but will keep it under review.</p><p> </p> answering member constituency Mid Norfolk answering member printed George Freeman question first answered 12/09/2014 10:16:45 answering member 4020 label Biography information for George Freeman
tabling member	4005 label Biography information for Bob Blackman