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<p>The steps that the Animals in Science Regulation Unit (ASRU) takes to encourage
the replacement of the use of animals in scientific procedures are part of a wider
strategy on the rigorous application of the 3Rs principles – replacement, reduction
and refinement.</p><p>Procedures on animals are only authorised after an assessment
process, which is undertaken by the Home Office Inspectorate. All project licence
applicants are required to describe and justify why available non-animal alternative
methodologies could not be used to achieve their scientific objectives.</p><p>In 2018
ASRU signed a Memorandum of Understanding with the National Centre for the 3Rs (NC3Rs)
to support the uptake of 3Rs approaches. The NC3Rs leads the discovery and application
of new technologies and approaches to replace, reduce and refine the use of animals
in scientific procedures. ASRU supports the NC3Rs drive to accelerate the development
and use of models and tools, based on the latest science and technologies, to address
important scientific questions without the use of animals.</p>
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