|
answer text |
<p>NHS England has advised that it develops treatment criteria for cancer and other
high cost drugs to support implementation of National Institute for Health and Care
Excellence (NICE) guidance and to ensure approved treatments are available as intended,
with access funded consistently across the country. These criteria are developed by
relevant expert clinical advisers, drawn from NHS England’s 42 Clinical Reference
Groups (CRGs). These CRGs have been established to support clinical commissioning
across the entire specialised commissioning portfolio.</p><p>In the case of NICE Technology
Appraisal TA429 for ibrutinib in previously treated chronic lymphocytic leukaemia
and untreated chronic lymphocytic leukaemia with 17p deletion or TP53 mutation, NICE
issued the following statement on 8 June 2018:</p><p><strong> </strong>“Given the
evidence that was considered by the NICE appraisal committee, we consider it reasonable
for the guidance to be read as referring to those patients considered unsuitable for
retreatment. Because unsuitability for retreatment is not defined in the guidance,
we consider it appropriate for NHS England, as the commissioner, to take clinical
advice in order to do so.”</p><p>NHS England took clinical advice in setting the specific
treatment criteria linked to this appraisal and we are advised that the criteria were
derived from the main study that had underpinned the NICE guidance and are consistent
with guidance issued by the European Society for Medical Oncology last updated in
June 2017. Between January 2017 and May 2018, nearly 1,000 patients were registered
to receive treatment with ibrutinib in this indication. This is in line with NICE’s
estimates that 700 adults per year would be eligible for treatment as a result of
its guidance.</p><p>However, NHS England has further advised that it is more than
willing to receive and review by the end of July, any further evidence that patients
and clinicians wish to submit on this matter. The evidence will first be considered
by NHS England’s Chemotherapy CRG, with advice and recommendations from this group
then being submitted to the National Medical Director, Professor Steve Powis, for
consideration.</p><p>During 2017/18, 1,193 Individual Funding Requests were considered
by NHS England. An analysis of how may related to treatments for blood cancer has
not been conducted.</p><p> </p>
|
|