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<p>In 2010, the coalition government made a commitment to work to reduce the use of
animals in scientific research and a delivery plan has been published. The plan shows
how alternative methods can deliver fast, high-quality research that <br>also boosts
economic growth. <br><br>Since the Plan was published, a wealth of significant new
research and knowledge dissemination on the 3Rs - Replacement, Refinement and Reduction
- has been completed. It includes the launch of the first products from the National
Centre for Replacement, Refinement and Reduction of Animals in Research (NC3Rs) open
innovation programme CRACK IT, a £4 million<br>competition run by Innovate UK and
the NC3Rs to fund the commercialisation of non-animal technologies.<br><br>There is
also the publication of important new studies on veterinary and human vaccine testing
by Defra and Public Health England which have identified scope to reduce the numbers
of animals used in developing vaccines. New joint working by the Royal Society for
the Prevention of Cruelty to Animals and the Home Office has additionally produced
refined testing models to reduce animal <br>suffering.<br><br>We have taken major
steps to encourage greater international adoption of 3Rs techniques, including a ground-breaking
programme of knowledge-sharing with regulators and life science associations in China
led by the Animals in Science Regulation Unit. In addition, we have published collaborative
research across the global life sciences sector led by the NC3Rs and the UK’s Medicines
and <br>Healthcare Products Regulatory Agency to minimise the use of recovery animals
in pharmaceutical development.</p><p> </p><p> </p><p> </p>
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