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<p>With reference to the report entitled Annual Statistics of Scientific Procedures
on Living Animals Great Britain 2019, published in July 2020, the types of products
included in blood-based products and other products under routine production can include
serum, plasma, antibodies and pathogens.</p><p>The returns of data from establishments
for the production of the Annual Statistics of Scientific Procedures on Living Animals
in Great Britain has not requested specific data which would allow the calculation
of the proportion of ‘other products’ that were for the production of monoclonal or
polyclonal antibodies.</p><p>All applications for the use of animals in science are
subject to a harm-benefit analysis, undertaken by the Home Office Inspectorate, to
ensure that any harm that may be caused to the animals is justified by the expected
benefits for humans, animals or the environment. The UK’s rigorous regulatory system
requires that no testing takes place if there is a validated non-animal alternative
that would achieve the scientific outcomes sought. Project licence proposals for research
on animals for which there is no non-animal alternative must comply fully with the
principles of the 3Rs: replacement, reduction and refinement.</p>
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