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<p>The National Institute for Health and Care Excellence (NICE) is responsible for
the review of the methods it uses in the development of its technology appraisal and
highly specialised technology recommendations in England. NICE has advised that additional
factors and modifiers that may affect NICE’s decisions, including factors relevant
to orphan medicines and medicines that substantially improve health and/or life expectancy,
are being considered within its methods review. This review will give consideration
to approaches in other health technology assessment bodies, including the devolved
administrations.</p>
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