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<p>Second species testing is required to ensure drugs are safe for patient use. The
standards for second species testing, and other types of regulatory testing, are regularly
reviewed, updated and set by experts as part of our UK commitment to international
regulation.</p><p> </p><p>The UK maintains a rigorous regulatory system which ensures
that animal research and testing is carried out only where no practicable alternatives
exist and under controls which keep suffering to a minimum. The Home Office ensures
all research proposals are compliant with the principles of Replacement, Reduction
and Refinement (the 3Rs).</p>
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