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<p>A recent study demonstrated a two-dose vaccine efficacy of 95% for the Pfizer/Biotech
COVID-19 vaccine, with a second dose delivered between 19 and 42 days. The Joint Committee
on Vaccination and Immunisation (JCVI) has reviewed evidence on the Pfizer/BioNTech
COVID-19 vaccine and advised an interval of up to 12 weeks between doses. The considerations
of the JCVI on extended intervals has been published, and is available here: <a href="https://www.gov.uk/government/publications/prioritising-the-first-covid-19-vaccine-dose-jcvi-statement"
target="_blank">https://www.gov.uk/government/publications/prioritising-the-first-covid-19-vaccine-dose-jcvi-statement</a></p><p>Using
data available from clinical trials, Public Health England estimated that vaccine
efficacy from the first dose of the Pfizer/BioNTech vaccine is approximately 89%.
This is the efficacy calculated 15 to 21 days after the first dose. The estimate for
15 to 28 days is 91% which includes seven days after the second dose, but is prior
to the time protection that may be expected from the second dose. There is no estimate
of efficacy for a single dose beyond 21 days, but the JCVI’s view is that protective
immunity from the first dose likely lasts for a duration of 12 weeks.</p>
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