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<p>The treatment of pernicious anaemia, the result of a vitamin B12 (cobalamin) deficiency,
is well established and reported in the British Committee for Standards in Haematology
(BCSH) document, <em>Guidelines for the diagnosis and treatment of Cobalamin and Folate
disorders</em>, which was updated in May 2014.</p><p> </p><p> </p><p> </p><p>Current
clinical practice within the United Kingdom is to treat pernicious anaemia with Vitamin
B12 intramuscular injections. The guideline states that standard maintenance therapy
for patients presenting without neurological symptoms is 1,000 microgrammes every
three months. Those with initial neurological symptoms should receive 1,000 microgrammes
every two months. The guideline can be found via the BCSH website at the following
link:</p><p> </p><p> </p><p> </p><p><a href="http://www.bcshguidelines.com/" target="_blank">www.bcshguidelines.com</a></p><p>
</p><p> </p><p> </p><p>However, the frequency with which vitamin B12 injections are
provided to patients with pernicious anaemia is matter for individual clinicians,
taking into account the relevant clinical guidance, the prescribed dose and the patient’s
response to the treatment.</p><p> </p>
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