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<p>The Government does not hold the information you have requested. The Home Office
has published advisory notes on recording and reporting actual severity. From data
collected, the Home Office will provide clarity on the burden of harm and, over time,
should give an indication of the effectiveness of refinement methods, particularly
for the most severe procedures.</p><p>It is important to note that procedures classified
as severe represent only a small percentage of the total.</p><p>The National Centre
for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs) was established
by the Government in May 2004 to advance and promote the Replacement, Refinement and
Reduction of animals used in research and testing (the 3Rs). The NC3Rs primarily receives
Government funding through BIS from the science and research ring-fenced budget via
the Medical Research Council (MRC) and Biotechnology and Biological Sciences Research
Council (BBSRC). The projected budget for the NC3Rs is £7.88m in 2014/15 and £7.84m
in 2015/16.</p><p>BBSRC also provides further funding for the 3Rs under its responsive
mode schemes, and the MRC and Engineering and Physical Sciences Research Council support
research projects which contribute to the development of new knowledge and new methods
that help replace or refine animal use. However, figures on future spend are not available.</p><p>For
a detailed breakdown of past funding I refer my hon. Friend to the answer I gave to
the hon. Member for Brighton, Pavilion on 11 March 2014, Official Report, column reference
167W.</p>
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