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<p>The article adds to the growing body of evidence that cancer genes and mechanisms
are altered by mutations in non-coding DNA, this is approximately 95% of the genome
which does not contain code for a protein. Analysis of whole genome sequencing data
can provide information on how mutations in both coding and non-coding regions relate
to cancer and other diseases.</p><p>In 2018, the Government committed to sequencing
at least one million whole genome equivalents over the next five years and this will
provide the data for further analysis of the contribution of both coding and non-coding
DNA to disease processes.</p>
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