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63787
star this property registered interest false more like this
unstar this property date less than 2014-06-24more like thismore than 2014-06-24
star this property answering body
Department for Business, Innovation and Skills more like this
star this property answering dept id 26 more like this
star this property answering dept short name Business, Innovation and Skills more like this
star this property answering dept sort name Business, Innovation and Skills more like this
star this property hansard heading Advisory Bodies more like this
star this property house id 2 more like this
star this property legislature
25277
star this property pref label House of Lords more like this
star this property question text To ask Her Majesty's Government what quality control and audit procedures are in place to ensure that their advisory committees perform to the highest standards, that they are using up-to-date methodology and science, and that their advice is sound and accepted by the broader scientific community. more like this
star this property tabling member printed
The Countess of Mar more like this
star this property uin HL571 more like this
star this property answer
answer
unstar this property is ministerial correction false more like this
star this property date of answer less than 2014-07-08more like thismore than 2014-07-08
star this property answer text <p> </p><p><em>All committees operate according to the guidelines and standards outlined in the </em>Code of Practice for Science Advisory Committees (CoPSAC[1]). Any advisory committee that is classified as a Non-Departmental Public Body (NDPB) is also subject to <em>formal Cabinet Office procedures including a full triennial review. </em></p><p><em> </em></p><p> </p><p>CoPSAC is underpinned by The Principles of Scientific Advice to Government', published in 2010 (Annex A to CoPSAC), and the ‘Nolan' principles for public life (the “Seven Principles of Public Life” (Annex C).</p><p> </p><p> </p><p>The principles “provide a foundation on which independent scientific advisers and government departments should base their operations and interactions”. Members are also expected to abide by the Nolan Principles, which include the principles of objectivity and accountability.</p><p> </p><p> </p><p>Any “issues of concern over the application of the Principles, or other guidance” should be raised to the Chief Scientific Adviser. “If the matter of concern cannot be effectively resolved or is especially serious CSAs should approach the Government Chief Scientific Adviser (GCSA) and Ministers should approach the GCSA and the Minister for Science. The matter will be examined against a clear set of criteria, which include a breach of the Principles or CoPSAC.”</p><p> </p><p><strong> </strong></p><p> </p><p> </p><p> </p><p> </p><p> </p><br /><p>[1] <a href="https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/278498/11-1382-code-of-practice-scientific-advisory-committees.pdf" target="_blank">https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/278498/11-1382-code-of-practice-scientific-advisory-committees.pdf</a></p><p> </p>
star this property answering member printed Viscount Younger of Leckie more like this
star this property question first answered
less than 2014-07-08T15:23:07.1810649Zmore like thismore than 2014-07-08T15:23:07.1810649Z
star this property answering member
4169
star this property label Biography information for Viscount Younger of Leckie more like this
star this property tabling member
1861
unstar this property label Biography information for The Countess of Mar remove filter
63788
star this property registered interest false more like this
unstar this property date less than 2014-06-24more like thismore than 2014-06-24
star this property answering body
Department for Business, Innovation and Skills more like this
star this property answering dept id 26 more like this
star this property answering dept short name Business, Innovation and Skills more like this
star this property answering dept sort name Business, Innovation and Skills more like this
star this property hansard heading Advisory Bodies more like this
star this property house id 2 more like this
star this property legislature
25277
star this property pref label House of Lords more like this
star this property question text To ask Her Majesty's Government whether their advisory committees, if they need to undertake a review for which they do not have the expertise, are permitted to commission organisations that specialise in that field. more like this
star this property tabling member printed
The Countess of Mar more like this
star this property uin HL572 more like this
star this property answer
answer
unstar this property is ministerial correction false more like this
star this property date of answer less than 2014-07-08more like thismore than 2014-07-08
star this property answer text <p> </p><p /> <p>There is nothing in the Code of Practice for Science Advisory Committees (CoPSAC[1]) that prevents a committee from commissioning additional advice from experts, and committees are encouraged to “seek a wide range of advice from the best sources, particularly when there is uncertainty”.</p><p /> <p> </p><p /> <p> </p><p /> <p> </p><p /> <p>CoPSAC states “Where a SAC lacks the relevant expertise for a particular project or task (as opposed to the committee's on-going work), the committee can co-opt appropriate experts or establish sub-groups to include such people on an ad hoc, time-limited basis”.</p><p /> <p> </p><p /> <p> </p><p /> <p> </p><p /> <p> </p><p /> <p> </p><p /> <p> </p><p /> <p> </p><p /> <p> </p><p /> <p> </p><p /> <p> </p><p /> <p> </p><p /> <br /> <p>[1]<a href="https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/278498/11-1382-code-of-practice-scientific-advisory-committees.pdf" target="_blank">https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/278498/11-1382-code-of-practice-scientific-advisory-committees.pdf</a></p><p /> <p> </p><p /> <p> </p><p /> <br /> <p>[1]<a href="https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/278498/11-1382-code-of-practice-scientific-advisory-committees.pdf" target="_blank">https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/278498/11-1382-code-of-practice-scientific-advisory-committees.pdf</a></p><p> </p><p> </p>
star this property answering member printed Viscount Younger of Leckie more like this
star this property question first answered
less than 2014-07-08T14:53:13.261755Zmore like thismore than 2014-07-08T14:53:13.261755Z
star this property answering member
4169
star this property label Biography information for Viscount Younger of Leckie more like this
star this property tabling member
1861
unstar this property label Biography information for The Countess of Mar remove filter
63789
star this property registered interest false more like this
unstar this property date less than 2014-06-24more like thismore than 2014-06-24
star this property answering body
Department for Business, Innovation and Skills more like this
star this property answering dept id 26 more like this
star this property answering dept short name Business, Innovation and Skills more like this
star this property answering dept sort name Business, Innovation and Skills more like this
star this property hansard heading Advisory Bodies more like this
star this property house id 2 more like this
star this property legislature
25277
star this property pref label House of Lords more like this
star this property question text To ask Her Majesty's Government how scientists are appointed to their advisory committees; how they ensure that an appropriate range of expertise and experience is represented on those committees; and how they ensure that the best scientists apply for membership of the committees. more like this
star this property tabling member printed
The Countess of Mar more like this
star this property uin HL573 more like this
star this property answer
answer
unstar this property is ministerial correction false more like this
star this property date of answer less than 2014-07-08more like thismore than 2014-07-08
star this property answer text <p> </p><p>The Code of Practice for Science Advisory Committees (CoPSAC[1]) lays out the procedures for appointment to Committees.</p><p> </p><p>CoPSAC indicates that the arrangements for the appointment of Committee members and the lines of accountability should be set out in each Committee's Terms of Reference.</p><p> </p><br /><p>[1]<a href="https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/278498/11-1382-code-of-practice-scientific-advisory-committees.pdf" target="_blank">https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/278498/11-1382-code-of-practice-scientific-advisory-committees.pdf</a></p><p> </p> more like this
star this property answering member printed Viscount Younger of Leckie more like this
star this property question first answered
less than 2014-07-08T14:53:54.6005833Zmore like thismore than 2014-07-08T14:53:54.6005833Z
star this property answering member
4169
star this property label Biography information for Viscount Younger of Leckie more like this
star this property tabling member
1861
unstar this property label Biography information for The Countess of Mar remove filter
63790
star this property registered interest false more like this
unstar this property date less than 2014-06-24more like thismore than 2014-06-24
star this property answering body
Department for Business, Innovation and Skills more like this
star this property answering dept id 26 more like this
star this property answering dept short name Business, Innovation and Skills more like this
star this property answering dept sort name Business, Innovation and Skills more like this
star this property hansard heading Advisory Bodies more like this
star this property house id 2 more like this
star this property legislature
25277
star this property pref label House of Lords more like this
star this property question text To ask Her Majesty's Government what recourse is available to members of the public who wish to complain about the practice and outcome of scientific inquiries conducted by government advisory committees. more like this
star this property tabling member printed
The Countess of Mar more like this
star this property uin HL574 more like this
star this property answer
answer
unstar this property is ministerial correction false more like this
star this property date of answer less than 2014-07-08more like thismore than 2014-07-08
star this property answer text <p> </p><p>Members of the public may write to the Chair of the advisory committee. If necessary, complaints can be escalated in writing to the Chief Scientific Advisor for the department in question, or the Government Chief Scientific Adviser.</p><p> </p><p> </p><p> </p><p> </p><p> </p> more like this
star this property answering member printed Viscount Younger of Leckie more like this
star this property question first answered
less than 2014-07-08T14:53:32.2722204Zmore like thismore than 2014-07-08T14:53:32.2722204Z
star this property answering member
4169
star this property label Biography information for Viscount Younger of Leckie more like this
star this property tabling member
1861
unstar this property label Biography information for The Countess of Mar remove filter
350104
star this property registered interest false more like this
unstar this property date less than 2015-06-11more like thismore than 2015-06-11
star this property answering body
Department for International Development more like this
star this property answering dept id 20 more like this
star this property answering dept short name International Development more like this
star this property answering dept sort name International Development more like this
star this property hansard heading West Africa: Ebola more like this
star this property house id 2 more like this
star this property legislature
25277
star this property pref label House of Lords more like this
star this property question text To ask Her Majesty’s Government what has been the total cost so far of providing personnel from the Ministry of Defence, National Health Service and Public Health England, and materials and medicines from the United Kingdom, to international efforts to tackle the recent ebola crisis. more like this
star this property tabling member printed
The Countess of Mar more like this
star this property uin HL418 more like this
star this property answer
answer
unstar this property is ministerial correction false more like this
star this property date of answer less than 2015-06-25more like thismore than 2015-06-25
star this property answer text <p>The UK has committed £427m to combat Ebola in West Africa, £373m for the ongoing response and £54m for early recovery programmes. This package of support covers the cost of UK operations, including Ministry of Defence assets and personnel, PHE clinicians, materials and medicines. Over £260 million has now been disbursed.</p> more like this
star this property answering member printed Earl of Courtown more like this
star this property question first answered
less than 2015-06-25T16:39:51.273Zmore like thismore than 2015-06-25T16:39:51.273Z
star this property answering member
3359
star this property label Biography information for The Earl of Courtown more like this
star this property tabling member
1861
unstar this property label Biography information for The Countess of Mar remove filter
654265
star this property registered interest false more like this
unstar this property date less than 2016-12-07more like thismore than 2016-12-07
star this property answering body
HM Treasury more like this
star this property answering dept id 14 more like this
star this property answering dept short name Treasury more like this
star this property answering dept sort name CaTreasury more like this
star this property hansard heading State Retirement Pensions: Females more like this
star this property house id 2 more like this
star this property legislature
25277
star this property pref label House of Lords more like this
star this property question text To ask Her Majesty’s Government what plans they have to support disabled women who rely for income on permanent health insurance policies that cover them until the age of 60, the default retirement age at the time the policies were bought, and will now not receive a state pension until the age of 65 to 67. more like this
star this property tabling member printed
The Countess of Mar more like this
star this property uin HL3930 more like this
star this property answer
answer
unstar this property is ministerial correction false more like this
star this property date of answer less than 2016-12-19more like thismore than 2016-12-19
star this property answer text <p>The decision to equalise the State Pension age for men and women dates back to the Pensions Act 1995. The Government provides benefits to support those unable to work to State Pension age due to a health condition or disability. People in this position may be eligible for Employment and Support Allowance, which provides income replacement for people with a health condition or disability, and Personal Independence Payment, which helps with some of the extra costs caused by long-term health or disability.</p> more like this
star this property answering member printed Lord Young of Cookham more like this
star this property question first answered
less than 2016-12-19T16:11:58.097Zmore like thismore than 2016-12-19T16:11:58.097Z
star this property answering member
57
star this property label Biography information for Lord Young of Cookham more like this
star this property tabling member
1861
unstar this property label Biography information for The Countess of Mar remove filter
895206
star this property registered interest false more like this
unstar this property date less than 2018-05-01more like thismore than 2018-05-01
star this property answering body
Cabinet Office more like this
star this property answering dept id 53 more like this
star this property answering dept short name Cabinet Office more like this
star this property answering dept sort name Cabinet Office more like this
star this property hansard heading Cervical Cancer more like this
star this property house id 2 more like this
star this property legislature
25277
star this property pref label House of Lords more like this
star this property question text To ask Her Majesty's Government what were the incidence rates of cervical cancer among (1) 18–49 year old women, and (2) women over the age of 50, in England for each year since 2011. more like this
star this property tabling member printed
The Countess of Mar more like this
star this property uin HL7466 more like this
star this property answer
answer
unstar this property is ministerial correction false more like this
star this property date of answer less than 2018-05-15more like thismore than 2018-05-15
star this property answer text <p>The information requested falls within the responsibility of the UK Statistics Authority. I have asked the Authority to reply.</p><p> </p><p><strong>Letter from John Pullinger CB, National Statistician, to The Countess of Mar, dated 3 May 2018.</strong></p><p> </p><p>Dear Lady Mar,</p><p> </p><p>As National Statistician and Chief Executive of the UK Statistics Authority, I am replying to your Parliamentary Question asking what were the incidence rates of cervical cancer among (1) 18-49 year old women, and (2) women over the age of 50, in England for each year since 2011 <strong>(HL7466)</strong>.</p><p> </p><p>The Office for National Statistics (ONS), in collaboration with Public Health England, publishes the number of cancer cases registered (incidence) in England in each calendar year, as part of its Cancer Statistics Registrations, England (Series MB1) release. The latest available cancer incidence data published by ONS are provisional figures for 2016[1]. The provisional 2016 release does not contain a refreshed back series of cancer incidence, which would consider the continual accrual of late registrations. Therefore, the historic figures (from 2011 to 2015) below are based on the 2015 National Statistics release[2].</p><p> </p><p>Cervical cancer is defined using International Classification of Diseases, 10<sup>th</sup> edition (ICD-10) code C53 (malignant neoplasm of cervix uteri). <strong>Table 1</strong> overleaf provides the number and rate of women diagnosed cases of cervical cancer, (ICD-10: C53) by age group, in England from 2011 to 2016.</p><p> </p><p>While ONS does not hold cancer incidence data for Northern Ireland, Scotland or Wales, similar figures are published by the Northern Ireland Cancer Registry[3], the Scottish Cancer Registry[4] and the Welsh Cancer Intelligence and Surveillance Unit[5], respectively.</p><p> </p><p> </p><p>Yours sincerely,</p><p> </p><p><strong>John Pullinger </strong></p><p> </p><table><tbody><tr><td><p><strong> </strong></p></td><td><p> </p></td><td colspan="2"><p> </p></td><td colspan="2"><p> </p></td><td colspan="2"><p> </p></td><td colspan="2"><p> </p></td><td colspan="2"><p> </p></td></tr><tr><td rowspan="2"><p><strong>Age group</strong></p></td><td><p><strong> </strong></p></td><td colspan="11"><p><strong>Year of Registration</strong></p></td></tr><tr><td><p><strong> </strong></p></td><td colspan="2"><p><strong>2011</strong></p></td><td colspan="2"><p><strong>2012</strong></p></td><td colspan="2"><p><strong>2013</strong></p></td><td colspan="2"><p><strong>2014</strong></p></td><td colspan="2"><p><strong>2015</strong></p></td><td><p><strong>2016<sup>p</sup></strong></p></td></tr><tr><td><p>18-49</p></td><td><p>Count</p></td><td colspan="2"><p>1,576</p></td><td colspan="2"><p>1,555</p></td><td colspan="2"><p>1,642</p></td><td colspan="2"><p>1,655</p></td><td colspan="2"><p>1,609</p></td><td><p>1,590</p></td></tr><tr><td><p>50+</p></td><td><p>Count</p></td><td colspan="2"><p>979</p></td><td colspan="2"><p>989</p></td><td colspan="2"><p>1,037</p></td><td colspan="2"><p>950</p></td><td colspan="2"><p>906</p></td><td><p>1,003</p></td></tr><tr><td><p> </p></td><td><p> </p></td><td colspan="2"><p><strong> </strong></p></td><td colspan="2"><p><strong> </strong></p></td><td colspan="2"><p><strong> </strong></p></td><td colspan="2"><p><strong> </strong></p></td><td colspan="2"><p><strong> </strong></p></td><td><p><strong> </strong></p></td></tr><tr><td><p>18-49</p></td><td><p>Rate</p></td><td colspan="2"><p>13.4</p></td><td colspan="2"><p>13.3</p></td><td colspan="2"><p>14.0</p></td><td colspan="2"><p>14.2</p></td><td colspan="2"><p>13.8</p></td><td><p>13.6</p></td></tr><tr><td><p>50+</p></td><td><p>Rate</p></td><td colspan="2"><p>10.1</p></td><td colspan="2"><p>10.0</p></td><td colspan="2"><p>10.4</p></td><td colspan="2"><p>9.3</p></td><td colspan="2"><p>8.7</p></td><td><p>9.5</p></td></tr><tr><td><p>Notes:</p></td><td><p> </p></td><td><p> </p></td><td colspan="2"><p> </p></td><td colspan="2"><p> </p></td><td colspan="2"><p> </p></td><td colspan="2"><p> </p></td><td colspan="2"><p> </p></td></tr><tr><td colspan="13"><p>1. Cervical cancer is defined according to the International Classification of Diseases, Tenth Revision (ICD-10) as C53.</p></td></tr><tr><td colspan="2"><p>p Provisional figures.</p></td><td><p> </p></td><td colspan="2"><p> </p></td><td colspan="2"><p> </p></td><td colspan="2"><p> </p></td><td colspan="2"><p> </p></td><td colspan="2"><p> </p></td></tr><tr><td><p> </p></td><td><p> </p></td><td><p> </p></td><td colspan="2"><p> </p></td><td colspan="2"><p> </p></td><td colspan="2"><p> </p></td><td colspan="2"><p> </p></td><td colspan="2"><p> </p></td></tr><tr><td colspan="3"><p><em>Source: Office for National Statistics</em></p></td><td colspan="2"><p> </p></td><td colspan="2"><p> </p></td><td colspan="2"><p> </p></td><td colspan="2"><p> </p></td><td colspan="2"><p> </p></td></tr></tbody></table><p><strong>Table 1: Incidence counts and rates per 100,000 women of cervical cancer by age group, England, 2011 to 2016<sup>1</sup></strong></p><p><strong> </strong></p><p>[1]<a href="https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/cancerregistrationstatisticsengland/2016" target="_blank">https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/cancerregistrationstatisticsengland/2016</a></p><p>[2]<a href="https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/cancerregistrationstatisticsengland/2015" target="_blank">https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/cancerregistrationstatisticsengland/2015</a></p><p>[3] <a href="http://www.qub.ac.uk/research-centres/nicr/" target="_blank">http://www.qub.ac.uk/research-centres/nicr/</a></p><p>[4] <a href="http://www.isdscotland.org/Health-Topics/Cancer/" target="_blank">http://www.isdscotland.org/Health-Topics/Cancer/</a></p><p>[5] <a href="http://www.wcisu.wales.nhs.uk/home" target="_blank">http://www.wcisu.wales.nhs.uk/home</a></p>
star this property answering member printed Lord Young of Cookham more like this
star this property question first answered
less than 2018-05-15T16:30:44.79Zmore like thismore than 2018-05-15T16:30:44.79Z
star this property answering member
57
star this property label Biography information for Lord Young of Cookham more like this
star this property tabling member
1861
unstar this property label Biography information for The Countess of Mar remove filter
78304
star this property registered interest false more like this
unstar this property date less than 2014-07-16more like thismore than 2014-07-16
star this property answering body
Cabinet Office more like this
star this property answering dept id 53 more like this
star this property answering dept short name Cabinet Office more like this
star this property answering dept sort name Cabinet Office more like this
star this property hansard heading Alzheimer's Disease more like this
star this property house id 2 more like this
star this property legislature
25277
star this property pref label House of Lords more like this
star this property question text To ask Her Majesty’s Government how many deaths in the United Kingdom were attributed to Alzheimer’s disease in 1970, 1982 and 2013. more like this
star this property tabling member printed
The Countess of Mar more like this
star this property uin HL1194 more like this
star this property answer
answer
unstar this property is ministerial correction false more like this
star this property date of answer less than 2014-07-21more like thismore than 2014-07-21
star this property answer text <p>The information requested falls within the responsibility of the UK Statistics Authority. I have asked the Authority to reply.</p><p> </p> more like this
star this property answering member printed Lord Wallace of Saltaire more like this
star this property question first answered
less than 2014-07-21T14:28:33.8065954Zmore like thismore than 2014-07-21T14:28:33.8065954Z
star this property answering member
1816
star this property label Biography information for Lord Wallace of Saltaire more like this
star this property attachment
1
star this property file name PQ HL1194 ONS 323.pdf more like this
star this property title ONS Letter to PEER more like this
star this property tabling member
1861
unstar this property label Biography information for The Countess of Mar remove filter
347943
star this property registered interest false more like this
unstar this property date less than 2015-06-02more like thismore than 2015-06-02
star this property answering body
Department of Health more like this
star this property answering dept id 17 more like this
star this property answering dept short name Health more like this
star this property answering dept sort name Health more like this
star this property hansard heading Human Papillomavirus: Vaccination more like this
star this property house id 2 more like this
star this property legislature
25277
star this property pref label House of Lords more like this
star this property question text To ask Her Majesty’s Government, to date, how many adverse reactions to (1) Cervarix, (2) Gardasil and (3) generic human papilloma virus vaccines have been reported to the Medicines and Healthcare products Regulatory Agency; for each category, how many of those reports are of serious adverse reactions; and what age-specific rate those figures represent. more like this
star this property tabling member printed
The Countess of Mar more like this
star this property uin HL229 more like this
star this property answer
answer
unstar this property is ministerial correction true more like this
star this property date of answer less than 2015-06-16more like thismore than 2015-06-16
star this property answer text <p>A total of 8,243 suspected adverse drug reaction (ADR) reports with human papilloma virus (HPV) vaccines have been reported to the Medicines and Healthcare products Regulatory Agency (MHRA), via the Yellow Card Scheme, up to 3 June 2015.</p><p> </p><p> </p><p> </p><p>To date, more than 8 million doses of HPV vaccine have been given across the United Kingdom as part of the routine immunisation programme. The MHRA does not hold data on age-specific vaccine usage, and therefore age-specific reporting rates cannot be calculated.</p><p> </p><p> </p><p> </p><p>It is important to note that a Yellow Card report is not proof of a side effect occurring, but a suspicion by the reporter that the vaccine may have been the cause. Yellow Card data cannot be used as a reliable indicator of the frequency of suspected ADRs to vaccines or medicines. The level of ADR reporting may fluctuate between given years due to a variety of reasons such as a medicine being new (reporting rates are generally higher when a product is first introduced), stimulated interest/publicity and variations in exposure to the medicine.</p><p> </p><p> </p><p> </p><p>The possible known side effects, and the frequency, are listed in the product information which is provided with the vaccines. The vast majority of the 8,243 ADRs relate to the known risks of vaccination that are well-described in the available product information. The proportion of suspected ADRs for HPV vaccines that were reported as serious (32%) is less than the proportion reported as serious for other routinely used vaccines (68% overall) during the same time period. The expected benefits in protecting against HPV-related mortality and disease outweigh the known side effects of HPV vaccine.</p><p> </p><p> </p><p> </p><p>The following table provides a breakdown of UK suspected spontaneous ADRs received via the Yellow Card Scheme in association with the HPV vaccine. The MHRA does not hold data on age-specific vaccine usage, and therefore age-specific reporting rates cannot be calculated.</p><p> </p><p> </p><p> </p><table><tbody><tr><td><p>Vaccine Brand</p></td><td><p>Total number of reports</p></td><td><p>Number of serious reports (% of total)</p></td><td><p>Reporting rate per 1000 doses (serious reporting rates per 1000)</p></td></tr><tr><td><p>Cervarix</p></td><td><p>6,266</p></td><td><p>1,768 (28%)</p></td><td><p><ins class="ministerial">n/a **</ins><del class="ministerial">0.78 (0.22)</del></p></td></tr><tr><td><p>Gardasil</p></td><td><p>1,471</p></td><td><p>504 (34%)</p></td><td><p><ins class="ministerial">n/a **</ins><del class="ministerial">0.18 (0.06)</del></p></td></tr><tr><td><p>HPV Brand unspecified</p></td><td><p>507</p></td><td><p>326 (64%)</p></td><td><p><ins class="ministerial">n/a ** </ins><del class="ministerial">0.06 (0.04)</del></p></td></tr><tr><td><p>Total for Human Papilloma virus vaccines</p></td><td><p>*8,244</p></td><td><p>2,598 (32%)</p></td><td><p>1.03 (0.32)</p></td></tr></tbody></table><p> </p><p><em>Source:</em> MHRA sentinel database for adverse reactions.</p><p> </p><p>* It should be noted that the total number of reports received will not be equal to the totals in the table above as some reports of suspected adverse reactions may have included more than one vaccine.</p><p><ins class="ministerial">**Updated UK-wide brand-specific usage data are not available to MHRA at the time of writing based on a minimum of 8 million combined doses of Cervarix and Gardasil administered across the UK to date.</ins></p><p> </p><p><ins class="ministerial"> <p> </p><p> </p><p> </p></ins></p><p> </p><p> </p><p> </p><p> </p><p> </p><p>The seriousness criteria for ADR reporting were determined by a working group of the Council for International Organizations of Medical Sciences (CIOMS) and are defined as 6 possible categories which are explained on the Yellow Card. The MHRA asks reporters to select one of the following criteria by ticking the appropriate box on the Yellow Card: (1) patient died due to reaction; (2) life threatening; (3) resulted in hospitalisation or prolonged inpatient hospitalisation; (4) congenital abnormality; and (5) involved persistent or significant disability or incapacity; or (6) if the reaction was deemed medically significant. In addition to this, seriousness of reaction terms has also been defined by the MHRA in its medical dictionary. Therefore an ADR report can be serious because the reporter considers the reaction to be serious or because the reaction term itself is considered serious in the MHRA medical dictionary.</p><p> </p>
star this property answering member printed Lord Prior of Brampton more like this
star this property question first answered
less than 2015-06-16T14:35:02.313Zmore like thismore than 2015-06-16T14:35:02.313Z
star this property question first ministerially corrected
less than 2015-07-03T14:01:13.16Zmore like thismore than 2015-07-03T14:01:13.16Z
star this property answering member
127
star this property label Biography information for Lord Prior of Brampton more like this
star this property previous answer version
5462
star this property answering member printed Lord Prior of Brampton more like this
star this property answering member
127
star this property label Biography information for Lord Prior of Brampton more like this
star this property tabling member
1861
unstar this property label Biography information for The Countess of Mar remove filter
386923
star this property registered interest false more like this
unstar this property date less than 2015-07-01more like thismore than 2015-07-01
star this property answering body
Department of Health more like this
star this property answering dept id 17 more like this
star this property answering dept short name Health more like this
star this property answering dept sort name Health more like this
star this property hansard heading Vitamin B12 more like this
star this property house id 2 more like this
star this property legislature
25277
star this property pref label House of Lords more like this
star this property question text To ask Her Majesty’s Government what steps they are taking to find an alternative and reliable test to assess the vitamin B12 status of the population; and what level of false high results the current test provides. more like this
star this property tabling member printed
The Countess of Mar more like this
star this property uin HL1032 more like this
star this property answer
answer
unstar this property is ministerial correction false more like this
star this property date of answer less than 2015-07-14more like thismore than 2015-07-14
star this property answer text <p>The diagnosis and treatment of pernicious anaemia, the result of a vitamin B12 (cobalamin) deficiency, is well established and reported in the British Committee for Standards in Haematology (BCSH) guidance document, <em>Guidelines for the diagnosis and treatment of Cobalamin and Folate disorders</em>, which was updated in May 2014. A copy of the BCSH guidance document is attached.</p><p> </p><p>The BCSH operates independently of the Department and NHS England and produces evidence based guidelines for both clinical and laboratory haematologists on the diagnosis and treatment of haematological disease, drawing on the advice of expert consultants and clinical scientists practicing in the United Kingdom. It would be for the BCSH, not the Department, to consider whether any adjustments to current best practice, in the diagnosis and treatment of patients with pernicious anaemia were needed, including whether any new or additional tests were appropriate.</p><p> </p><p> </p><p> </p><p>The BCSH guidance sets out that cobalamin status is the recommended first line diagnostic test. The Department has no data relating to false positive results in relation to the test. The guidance also states that clinical picture is the most important factor in assessing the significance of the test results.</p><p> </p><p> </p><p> </p><p>When anaemia is diagnosed, most patients respond well to treatment through quarterly intramuscular injection of vitamin B12. Whilst some patients with pernicious anaemia might prefer to have more frequent injections, or for other forms of vitamin B12 to be self-administered, these are matters for individual patients to discuss with their general practitioners.</p><p> </p><p> </p><p> </p><p>Although the Medicines Healthcare products Regulatory Agency is currently reviewing claims made by some clinics that are administering vitamins and minerals intravenously for nutritional therapy purposes, the agency has not encountered any clinics making claims to treat pernicious anaemia. In addition, the Department does not have any information regarding patients purchasing additional supplies of B12 from unregulated sources.</p><p> </p><p> </p><p> </p><p>Regarding the mandatory fortification of flour with folic acid, the Scientific Advisory Committee on Nutrition recommended a number of measures to ensure monitoring and surveillance of the impact of fortification of flour, should it be implemented. This included appropriate systems to monitor any potential adverse effects, including cancer and a review of the evidence on benefits and postulated risks after five years. The National Diet and Nutrition Survey monitors folate intakes and the most recent data, which was published earlier this year, will be carefully considered alongside other information sources before any decision is made on mandatory fortification.</p><p> </p><p> </p><p> </p><p>The Department has made no assessment of the social and economic costs of misdiagnosis or late diagnosis of pernicious anaemia and other vitamin B12 deficiencies.</p><p> </p>
star this property answering member printed Lord Prior of Brampton more like this
star this property grouped question UIN
HL1033 more like this
HL1034 more like this
HL1035 more like this
HL1036 more like this
HL1042 more like this
star this property question first answered
less than 2015-07-14T15:00:41.673Zmore like thismore than 2015-07-14T15:00:41.673Z
star this property answering member
127
star this property label Biography information for Lord Prior of Brampton more like this
star this property attachment
1
star this property file name colbalamin and folate disorders.pdf more like this
star this property title BSCH Guidance more like this
star this property tabling member
1861
unstar this property label Biography information for The Countess of Mar remove filter