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156466
unstar this property registered interest false more like this
star this property date remove filter
star this property answering body
Cabinet Office more like this
star this property answering dept id 53 more like this
star this property answering dept short name Cabinet Office more like this
star this property answering dept sort name Cabinet Office more like this
star this property hansard heading In Vitro Fertilisation remove filter
unstar this property house id 2 more like this
star this property legislature
25277
star this property pref label House of Lords more like this
star this property question text To ask Her Majesty’s Government, further to the Written Answer by Earl Howe on 17 November (HL2643), what was the proportion of stillbirths and linked infant deaths as described in the previously provided table in which both of the two twins and each of the three triplets from the same pregnancy either similarly died in infancy or were stillborn. more like this
star this property tabling member printed
Lord Alton of Liverpool more like this
star this property uin HL2908 more like this
star this property answer
answer
unstar this property is ministerial correction false more like this
star this property date of answer less than 2014-11-21more like thismore than 2014-11-21
star this property answer text <p>The information requested falls within the responsibility of the UK Statistics Authority. I have asked the Authority to reply.</p><p> </p> more like this
star this property answering member printed Lord Wallace of Saltaire more like this
star this property question first answered
less than 2014-11-21T13:18:49.823Zmore like thismore than 2014-11-21T13:18:49.823Z
star this property answering member
1816
star this property label Biography information for Lord Wallace of Saltaire more like this
star this property attachment
1
star this property file name HL2908 ONS Letter - Lord Alton.pdf more like this
star this property title UK Statistics Authority more like this
star this property tabling member
738
star this property label Biography information for Lord Alton of Liverpool more like this
156283
unstar this property registered interest false more like this
star this property date remove filter
star this property answering body
Department of Health more like this
star this property answering dept id 17 more like this
star this property answering dept short name Health more like this
star this property answering dept sort name Health more like this
star this property hansard heading In Vitro Fertilisation remove filter
unstar this property house id 1 more like this
star this property legislature
25259
star this property pref label House of Commons more like this
star this property question text To ask the Secretary of State for Health, with reference to page 15 of Mitochondrial Donation: Government response to the consultation on draft regulations to permit the use of new treatment techniques to prevent the transmission of a serious mitochondrial disease from mother to child, published in July 2014, what the evidential basis is for the statement that donated mitochondrial DNA will not affect personal characteristics. more like this
star this property tabling member constituency Congleton more like this
star this property tabling member printed
Fiona Bruce more like this
star this property uin 215106 more like this
star this property answer
answer
unstar this property is ministerial correction false more like this
star this property date of answer less than 2014-11-25more like thismore than 2014-11-25
star this property answer text <p>Physical characteristics and personality traits are inherited from parents’ nuclear DNA. Whole mitochondrial DNA genome sequencing has revealed no evidence of nuclear genomic DNA inside mitochondria and data on the human genome available in the ENSEMBL and OMIM databases confirms that there is no nuclear genomic DNA in the mitochondria. The Revised Cambridge Reference Sequence of the Human Mitochondrial DNA, which can be found at:</p><p> </p><p> </p><p> </p><p><a href="https://wtoutlook.wellcome.ac.uk/OWA/redir.aspx?C=OY5Ca06YIkStrydor-fyawAWM0rJaNEIQZOF7ynJO3PqA3uFGov62nxpesH4_vBBclsLZLTfszc.&amp;URL=http%3a%2f%2fwww.mitomap.org%2fMITOMAP%2fHumanMitoSeq" target="_blank">http://www.mitomap.org/MITOMAP/HumanMitoSeq</a></p><p> </p><p> </p><p> </p><p>details the whole mitochondrial DNA genome sequence, the codons, the proteins and the genes encoded for. All genes encoded for by mitochondrial DNA are involved in energy production, rather than governing personal characteristics and traits.</p><p> </p><p> </p><p> </p><p>Any child born as a result of the use of mitochondrial donation techniques will be genetically unique and will have a natural combination of nuclear genes from both parents but not the mitochondrial donor. As mentioned by the Chief Medical Officer, mitochondrial DNA only encodes genes responsible for energy production and will not affect the child’s appearance, personality or any other personal characteristics.</p><p> </p>
star this property answering member constituency Battersea more like this
star this property answering member printed Jane Ellison more like this
star this property grouped question UIN 215107 more like this
star this property question first answered
less than 2014-11-25T17:31:22.86Zmore like thismore than 2014-11-25T17:31:22.86Z
star this property answering member
3918
star this property label Biography information for Jane Ellison more like this
star this property tabling member
3958
star this property label Biography information for Fiona Bruce more like this
156285
unstar this property registered interest false more like this
star this property date remove filter
star this property answering body
Department of Health more like this
star this property answering dept id 17 more like this
star this property answering dept short name Health more like this
star this property answering dept sort name Health more like this
star this property hansard heading In Vitro Fertilisation remove filter
unstar this property house id 1 more like this
star this property legislature
25259
star this property pref label House of Commons more like this
star this property question text To ask the Secretary of State for Health, whether the comments of the Chief Medical Officer of 10 November 2014 that children born through mitochondrial transfer techniques will only have the characteristics any other child would have in that family accord with the view of his Department; and if he will make a statement. more like this
star this property tabling member constituency Congleton more like this
star this property tabling member printed
Fiona Bruce more like this
star this property uin 215107 more like this
star this property answer
answer
unstar this property is ministerial correction false more like this
star this property date of answer less than 2014-11-25more like thismore than 2014-11-25
star this property answer text <p>Physical characteristics and personality traits are inherited from parents’ nuclear DNA. Whole mitochondrial DNA genome sequencing has revealed no evidence of nuclear genomic DNA inside mitochondria and data on the human genome available in the ENSEMBL and OMIM databases confirms that there is no nuclear genomic DNA in the mitochondria. The Revised Cambridge Reference Sequence of the Human Mitochondrial DNA, which can be found at:</p><p> </p><p> </p><p> </p><p><a href="https://wtoutlook.wellcome.ac.uk/OWA/redir.aspx?C=OY5Ca06YIkStrydor-fyawAWM0rJaNEIQZOF7ynJO3PqA3uFGov62nxpesH4_vBBclsLZLTfszc.&amp;URL=http%3a%2f%2fwww.mitomap.org%2fMITOMAP%2fHumanMitoSeq" target="_blank">http://www.mitomap.org/MITOMAP/HumanMitoSeq</a></p><p> </p><p> </p><p> </p><p>details the whole mitochondrial DNA genome sequence, the codons, the proteins and the genes encoded for. All genes encoded for by mitochondrial DNA are involved in energy production, rather than governing personal characteristics and traits.</p><p> </p><p> </p><p> </p><p>Any child born as a result of the use of mitochondrial donation techniques will be genetically unique and will have a natural combination of nuclear genes from both parents but not the mitochondrial donor. As mentioned by the Chief Medical Officer, mitochondrial DNA only encodes genes responsible for energy production and will not affect the child’s appearance, personality or any other personal characteristics.</p><p> </p>
star this property answering member constituency Battersea more like this
star this property answering member printed Jane Ellison more like this
star this property grouped question UIN 215106 more like this
star this property question first answered
less than 2014-11-25T17:31:22.937Zmore like thismore than 2014-11-25T17:31:22.937Z
star this property answering member
3918
star this property label Biography information for Jane Ellison more like this
star this property tabling member
3958
star this property label Biography information for Fiona Bruce more like this
156463
unstar this property registered interest false more like this
star this property date remove filter
star this property answering body
Department of Health more like this
star this property answering dept id 17 more like this
star this property answering dept short name Health more like this
star this property answering dept sort name Health more like this
star this property hansard heading In Vitro Fertilisation remove filter
unstar this property house id 2 more like this
star this property legislature
25277
star this property pref label House of Lords more like this
star this property question text To ask Her Majesty’s Government, further to the Written Answer by Earl Howe on 17 November (HL2643), whether the records held by the Human Fertilisation and Embryology Authority on foetal reductions carried out in the first trimester and early in the second trimester following in vitro fertilisation or donor insemination indicate that it has any significant impact on "the single biggest risk to the health and welfare of children born following fertility treatment"; if so, what is the effect and how it is represented numerically; and to what extent the recommendation that prevention of multiple pregnancies through single embryo transfer should be preferred to multi-foetal pregnancy reduction reflects a lack of efficacy of foetal reductions in reducing risks or emotional trauma associated with such a procedure. more like this
star this property tabling member printed
Lord Alton of Liverpool more like this
star this property uin HL2905 more like this
star this property answer
answer
unstar this property is ministerial correction false more like this
star this property date of answer less than 2014-12-02more like thismore than 2014-12-02
star this property answer text <p>The Human Fertilisation and Embryology Authority has advised that it has not undertaken such an analysis but that it plans to do so.</p><p> </p> more like this
star this property answering member printed Earl Howe more like this
star this property question first answered
less than 2014-12-02T12:41:51.237Zmore like thismore than 2014-12-02T12:41:51.237Z
star this property answering member
2000
star this property label Biography information for Earl Howe more like this
star this property tabling member
738
star this property label Biography information for Lord Alton of Liverpool more like this
156464
unstar this property registered interest false more like this
star this property date remove filter
star this property answering body
Department of Health more like this
star this property answering dept id 17 more like this
star this property answering dept short name Health more like this
star this property answering dept sort name Health more like this
star this property hansard heading In Vitro Fertilisation remove filter
unstar this property house id 2 more like this
star this property legislature
25277
star this property pref label House of Lords more like this
star this property question text To ask Her Majesty’s Government, further to the Written Answer by Earl Howe on 17 November (HL2642), whether they consider that any of the mitochondrial diseases listed in Annex D of the "Mitochondrial Donation" consultation document could ever arise from a nuclear gene defect; and if so, what is their assessment of the frequency with which it occurs and how that has been reflected when discussing mitochondrial diseases that may be candidates for pronuclear transfer or spindle-chromosomal complex transfer. more like this
star this property tabling member printed
Lord Alton of Liverpool more like this
star this property uin HL2906 more like this
star this property answer
answer
unstar this property is ministerial correction false more like this
star this property date of answer less than 2014-12-02more like thismore than 2014-12-02
star this property answer text <p>As stated in my Written Answer of 17 November 2014 (<em>Official Report</em>, col. WA59) the mitochondrial diseases listed in Annex D of the mitochondrial donation consultation document are diseases caused by an inherited mutation in mitochondrial DNA. As such, none of these diseases are caused by a nuclear gene defect. Mitochondrial disorders caused by a nuclear gene defect are distinct from those listed in Annex D.</p><p> </p> more like this
star this property answering member printed Earl Howe more like this
star this property question first answered
less than 2014-12-02T12:42:21.587Zmore like thismore than 2014-12-02T12:42:21.587Z
star this property answering member
2000
star this property label Biography information for Earl Howe more like this
star this property tabling member
738
star this property label Biography information for Lord Alton of Liverpool more like this