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175862

registered interest
date	27/01/2015
answering body	Department of Health
answering dept id	17
answering dept short name	Health
answering dept sort name	Health
hansard heading	IVF
house id	2
legislature	25277 pref label House of Lords
question text	To ask Her Majesty’s Government, further to the Written Answer by Earl Howe on 26 January 2015 (HL4064), why the Human Fertilisation and Embryology Authority (HFEA) does not consider that discussion of genetic modification, as it might be considered to apply to the creation of human admixed embryos, can usefully add to the debate on the definition of genetic modification in humans; whether the basis for the HFEA’s particular position is legal, scientific, doctrinal, ideological or pecuniary; whether the HFEA is capable of distinguishing between human embryos that have been genetically modified or not; if so, why it is unable to determine whether the generation of any human admixed embryos as defined under section 4A(6)(a) to (c) of the Human Fertilisation and Embryology Act 1990 would constitute genetic modification; and if not, how the HFEA is able to regulate such manipulation of human embryos.
tabling member printed	Lord Alton of Liverpool
uin	HL4442
answer	answer is ministerial correction date of answer 10/02/2015 answer text <p>We are advised that the Human Fertilisation and Embryology Authority (HFEA) does not believe that discussion of genetic modification, as it might be considered to apply to the creation of human admixed embryos, can usefully add to the debate on the definition of genetic modification in humans. This is because the current debate relates to the use of human eggs and embryos, which might be permitted for use in treatment, which would not involve the use of animal DNA, eggs or embryos.</p><p> </p><p> </p><p> </p><p>The HFEA has also advised that the regulatory framework enables the Authority to provide appropriate oversight of all embryos used in treatment and research.</p><p> </p> answering member printed Earl Howe question first answered 10/02/2015 17:25:40 answering member 2000 label Biography information for Earl Howe
tabling member	738 label Biography information for Lord Alton of Liverpool

175863

registered interest
date	27/01/2015
answering body	Department of Health
answering dept id	17
answering dept short name	Health
answering dept sort name	Health
hansard heading	IVF
house id	2
legislature	25277 pref label House of Lords
question text	To ask Her Majesty’s Government, further to the Written Answers by Earl Howe on 26 January 2015 (HL4063 and HL4228), how members of the Expert Panel convened by the Human Fertilisation and Embryology Authority (HFEA) were assured that the children were genetically normal in the absence of any further information when the published abstract only referred to a "normal karyotype" and there was no "data concerned" further to support this; whether each of the mitochondrial diseases listed in Annex D of the Department of Health’s consultation document entitled "Mitochondrial Donation" is associated with an abnormal karyotype; whether they will place in the Library of the House a full copy of the correspondence between the member of the HFEA’s Expert Panel and the Zhang research group; if not, why not; and on what date or dates the correspondence was shared with all other members of the HFEA’s Expert Panel.
tabling member printed	Lord Alton of Liverpool
uin	HL4443
answer	answer is ministerial correction date of answer 10/02/2015 answer text <p>I have nothing further to add to the answers given previously on the subject of the published abstract of the Zhang research group.</p><p> </p><p><strong> </strong></p><p> </p><p>We are advised that all of the mitochondrial diseases listed in the consultation document are due to point mutations or deletions and thus there is a normal karyotype.</p><p> </p> answering member printed Earl Howe question first answered 10/02/2015 17:27:29 answering member 2000 label Biography information for Earl Howe
tabling member	738 label Biography information for Lord Alton of Liverpool

175864

registered interest
date	27/01/2015
answering body	Department of Health
answering dept id	17
answering dept short name	Health
answering dept sort name	Health
hansard heading	IVF
house id	2
legislature	25277 pref label House of Lords
question text	To ask Her Majesty’s Government, further to the Written Answer by Earl Howe on 21 January (HL4011) regarding the challenges facing the National Health Service of tackling obesity, what assessment the Human Fertilisation and Embryology Authority (HFEA) has made of the impact of findings recently reported in the journal <i>Endocrinology</i> (Volume 155, Issue 11, pages 4554–67); and what data is held by the HFEA that would permit follow-up studies of children conceived via in vitro fertilisation, in order to establish whether or not trends observed in mice are similarly apparent in humans.
tabling member printed	Lord Alton of Liverpool
uin	HL4444
answer	answer is ministerial correction date of answer 10/02/2015 answer text <p>The Human Fertilisation and Fertilisation Authority (HFEA) has advised that it has not made an assessment of the impact of findings recently reported in the journal Endocrinology (Volume 155, Issue 11, pages 4554-67). However, the legislative framework allows the HFEA to hold data that can be linked to other databases holding height and weight data (for instance the Clinical Practice Research Datalink). Providing this linkage is performed by researchers at a United Kingdom institution, it would be permissible to carry out follow-up studies of children conceived via in vitro fertilisation, in order to establish whether or not the trend observed in mice is similarly apparent in humans.</p><p> </p> answering member printed Earl Howe question first answered 10/02/2015 15:49:21 answering member 2000 label Biography information for Earl Howe
tabling member	738 label Biography information for Lord Alton of Liverpool